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食管癌患者术后乳糜胸发生情况及其影响因素

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目的 探寻可能影响食管癌患者术后发生乳糜胸的因素,旨在降低临床食管癌患者术后乳糜胸发生风险.方法 纳入医院2019年1月至2021年12月收治的830例食管癌患者,依据患者术后有无发生乳糜胸进行分组.对比发生组与未发生组基线资料,探寻食管癌患者术后发生乳糜胸的影响因素.结果 830例食管癌患者中,术后发生乳糜胸30例,占比3.61%(30/830),将其纳入发生组;术后未发生乳糜胸800例,占比96.39%(800/830),将其纳入未发生组;发生组肿瘤直径(≥5 cm)、肿瘤病灶位置(中上段)、纵膈淋巴结肿大(是)、肿瘤分期(≥ Ⅲ期)占比均高于未发生组(P<0.05);经多项logistic回归分析结果显示,肿瘤直径、肿瘤病灶位置、纵膈淋巴结肿大及肿瘤分期均是食管癌术后发生乳糜胸的危险因素(OR>1,P<0.05).结论 肿瘤直径≥5 cm、肿瘤病灶位置处于中上段、纵膈淋巴结肿大及肿瘤分期≥Ⅲ期均是影响食管癌患者术后乳糜胸发生的因素,针对合并上述危险因素患者,临床可制定针对性干预手段,以降低食管癌患者术后乳糜胸发生风险.
Occurrence and Influencing Factors of Postoperative Chylothorax in Patients with Esophageal Cancer
Objective To explore the possible influencing factors of postoperative chylothorax in patients with esophageal cancer,in order to reduce the risk of postoperative chylothorax in patients with clinical esophageal cancer.Methods A total of 830 patients with esophageal cancer admitted to the hospital from January 2019 to December 2021 were enrolled.The patients were divided into groups according to whether or not they developed chylothorax after surgery,and the baseline data of the occurrence group and the non-occurrence group were compared to explore the factors affecting the postoperative occurrence of chylothorax in patients with esophageal cancer.Results There were 30 cases of chylothorax in 830 patients with esophageal cancer after operation,accounting for 3.61%(30/830),which were included in the occurrence group.There were 800 cases without chylothorax after operation,accounting for 96.39%(800/830),and they were included in the non-occurrence group.The proportion of tumor diameter(≥5 cm),tumor location(middle and upper segment),mediastinal lymph node enlargement(yes)and tumor stage(≥ Ⅲ)in the occurrence group was higher than that in the non-occurrence group(P<0.05).Multiple logistic regression analysis results showed that tumor diameter,tumor lesion location,mediastinal lymph node enlargement and tumor stage were all risk factors for chylothorax after esophageal cancer(OR>1,P<0.05).Conclusion Tumor diameter ≥5 cm,tumor lesion location in the upper middle segment,mediastinal lymph node enlargement,and tumor stage≥Ⅲ are all factors that affect the occurrence of postoperative chylothorax in esophageal cancer patients.Targeted intervention measures can be developed in clinical practice to reduce the risk of postoperative chylothorax in esophageal cancer patients with the combination of these risk factors.

esophageal cancerchylothoraxinfluencing factors

李悦华、贾佳、吴倩、邹其云、刘宝兴

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河南省肿瘤医院胸外二病区,河南郑州 450000

食管癌 乳糜胸 影响因素

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(4)
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