Association of the Serum 25-Hydroxy Vitamin D3 Level with the Pregnancy Outcomes of Artificial Insemination by Donor
Objective To explore the association of the 25-hydroxy vitamin D3[25(OH)D3)]level in the serum with the pregnancy outcome of artificial insemination by donor(AID).Methods A total of 279 infertile women that under AID and detection of serum 25(OH)D3 in the Department of Reproductive Medicine of Luoyang Central Hospital Affiliated to Zhengzhou University from January 2020 to June 2022 were selected.According the level of serum 25(OH)D3,the patients were divided into vitamin D deficiency groups[25(OH)D3＜30 μg·L-1,199 cases]and normal group[25(OH)D3≥30 μg·L-1,88 cases].The basic information and the rates of clinical pregnancy,rates of abortion and rate of live birth were compared between the two groups,and the factors affecting the early pregnancy outcome were investigated using binary logistic regression analysis.Results There were no statistically significant differences in natural cycle proportion,proportion of two operations,the number of ≥18 mm follicles,the age,body mass index,endometrial thickness of operating day,infertility years,number of sperm injected into the uterine cavity,does of Gn,the rate of clinical pregnancy,the rate of abortion and the rate of live birth between the two groups(P＞0.05),but anti-mullerian hormone between the two groups was significant differences(P＜0.05).Multivariate binary logistic regression model showed that 25(OH)D3 was not an independent factor affecting clinical pregnancy.Conclusion There was no correlation between serum 25(OH)D3 and clinical pregnancy outcome after AID.Age can be used as good indicator to predict the success rate of AID.
25-hydroxy vitamin D3artifical insemination by donorclinical pregnancy outcome
万方数据
