Diagnostic Efficacy of High-resolution CT Combined with Serum ESR and hs-CRP Levels Detection in Pneumoconiosis Combined with Pulmonary Tuberculosis
Objective To investigate the diagnostic efficiency of high resolution CT combined with serum erythrocyte sedimentation rate(ESR)and hypersensitive C-reactive protein(hs-CRP)on pneumoconiosis complicated with pulmonary tuberculosis.Methods A total of 112 patients diagnosed with pneumoconiosis received in the hospital from April 2021 to April 2023 were selected as research objects.All of them underwent high-resolution CT examination.The results of sputum tuberculin culture and purified protein derivative of tuberculin(PPD)test were used as the gold standard to analyze the diagnostic criteria of high-resolution CT for pneumoconiosis complicated with tuberculosis.Serum ESR and hs-CRP levels in patients with pneumoconiosis and pneumoconiosis combined with pulmonary tuberculosis were compared,and the diagnostic efficiency of high-resolution CT combined with serum ESR and hs-CRP levels in detecting pneumoconiosis combined with pulmonary tuberculosis was analyzed,and the risk of pulmonary tuberculosis in pneumoconiosis patients with different serum ESR and hs-CRP levels were analyzed.Results The incidence of pulmonary tuberculosis in 112 pneumoconiosis patients was 40.18％(45/112).The diagnostic sensitivity,specificity,accuracy,positive predictive value and negative predictive value of high-resolution CT were 91.11％,85.57％,88.39％,82.00％,91.11％,respectively.hs-CRP and ESR in pneumoconiosis patients were lower than those in pneumoconiosis patients with pulmonary tuberculosis(P＜0.05).Receiver operating characteristics(ROC)curve showed that the area under the curve(AUC)value of hs-CRP,ESR and high-resolution CT in the diagnosis of pneumoconiosis complicated with pulmonary tuberculosis was 0.814(95％CI:0.764-0.867),and the optimal diagnostic sensitivity and specificity were 93.33％and 89.55％,respectively.The risk of pulmonary tuberculosis in patients with high ESR and hs-CRP was 0.472 times and 0.403 times that of low ESR and HS-CRP(P＜0.05).Conclusion High-resolution CT combined with serum hs-CRP and ESR levels has high application value in the diagnosis of pneumoconiosis complicated with pulmonary tuberculosis,which can provide scientific data support for early clinical diagnosis and treatment.
万方数据
维普
