首页|改良的早期预警评分联合动脉血氧饱和度监测对门诊新型冠状病毒感染患者病情及预后的评估作用

改良的早期预警评分联合动脉血氧饱和度监测对门诊新型冠状病毒感染患者病情及预后的评估作用

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目的 评估改良的早期预警评分(MEWS)联合动脉血氧饱和度(SpO2)监测判断门诊新型冠状病毒感染(COVID-19)重症患者的可行性,探讨适用于门诊COVID-19患者病情评估的可行性预警模型.方法 回顾性收集2022年12月15日至2023年1月15日在郑州大学附属郑州中心医院新冠康复门诊就诊的COVID-19患者的一般资料,按照就诊前是否进行MEWS评分及SpO2监测分为对照组及校正MEWS评分组.应用受试者工作特征(ROC)曲线分析校正MEWS评分判断门诊COVID-19患者重症转归的灵敏度、特异度及最佳临界值;比较两组患者门诊就诊后15 d内重症转归率、病死率、住院前门诊停留时间、住院时间等指标.结果 校正MEWS评分预测门诊COVID-19患者就诊后15 d内重症转归的灵敏度为83.05%,特异度为87.32%,最佳临界值为4.5分;构成校正MEWS评分的各项因素中,SpO2对重症转归组分类的特征重要性最高达42.20%;相对于对照组,校正MEWS评分组重症转归率较低,门诊停留时间和住院时间较短(P<0.05),但两组病死率差异无统计学意义(P>0.05).结论 以SpO2作为校正因子的MEWS评分模型可有效识别潜在的门诊重症COVID-19患者并进行预警,这种预警作用可能有利于医疗人员采取更加积极的临床治疗决策,进而影响门诊COVID-19患者就诊后的临床转归和相关医疗经济指标.
Evaluation Effects of Modified Early Warning Score Combined with Arterial Oxygen Saturation Monitoring on the Condition and Prognosis of Outpatients with CO VID-19 Infection
Objective To evaluate the feasibility of modified early warning score(MEWS)combined with monitoring of oxygen saturation by arterial oxygen saturation(SpO2)in identifying outpatients with severe corona virus disease 2019(CO VID-19),in order to establish a feasible early-warning model applicable to the evaluation of the condition of outpatients with COVID-19.Methods A retrospective analysis was performed based on the collection of general data of patients with confirmed CO VID-19 who visited COVID-19 Rehabilitation Clinic in Zhengzhou Central Hospital Affiliated to Zhengzhou University from December 15,2022 to January 15,2023.Enrolled patients were divided into control group and corrected MEWS group according to whether MEWS scoring and SpO2 monitoring were performed before ambulatory treatment.The corrected MEWS was analyzed by the receiver operating characteristic(ROC)curve to predict the sensitivity,specificity and optimal cut-off value of the severe outcome in outpatients with COVID-19.Besides,the severe outcome rate,case fatality rate,length of outpatient stay in outpatient department before hospitalization,hospital stay and other indicators within 15 days after outpatient visits were compared between the two groups.Results The sensitivity,specificity and optimal cut-off value of the severe outcome in outpatients with COVID-19 predicted by the corrected MEWS was 83.05%,87.32%and 4.5 points,respectively.Among the factors that constitute the corrected MEWS,the feature importance ratio of SpO2 for the classification of the severe outcome group was up to 42.20%.Compared with the control group,the corrected MEWS group had lower severe outcome rate and shorter length of outpatient stay in outpatient and hospital stay(P<0.05),but there was no statistically difference in mortality rates between the two groups(P>0.05).Conclusion The MEWS scoring model revised by SpO2 as a correction factor can effectively identify potential severe COVID-19 outpatients and give early warning.Such early-warning effect may benefit more active clinical treatment decision-making by medical staff,thereby producing a positive effect on the clinical outcome of patients with COVID-19 after outpatient visits and relevant medical economic indicators.

novel coronavirusmodified early warning scoreoxygen saturationclinical outcomefatality rate

魏海英、张晓婷

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郑州大学附属郑州中心医院门诊办公室,河南郑州 450007

新型冠状病毒感染 改良的早期预警评分 氧饱和度 临床转归 病死率

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(5)
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