Correlation Between Glycosylated Hemoglobin Variation Index and Subclinical Hypothyroidism in Patients with Diabetes Mellitus Type 2
Objective To investigate the correlation between glycosylated hemoglobin variation index(HGI)and subclinical hypothyroidism(SCH)in patients with diabetes mellitus type 2(T2DM).Methods A retrospective study was conducted,including 56 T2DM patients with concurrent SCH who visited the Fifth Affiliated Hospital of Zhengzhou University from May 2020 to May 2023 as the occurrence group,and 56 T2DM patients without concurrent SCH who visited the hospital during the same period as the non-occurrence group.The baseline data and laboratory indicators of the two groups were compared,and the HGI value was calculated.The relationship between HGI and SCH in T2DM patients was discussed by point two column correlation analysis and receiver operating characteristic(ROC)curve.Results The female proportion,age,glycosylated hemoglobin(HbA1c)and HGI in the occurrence group were higher than those in the non-occurrence group(P＜0.05).Through point two column correlation analysis,it was found that HbA1c and HGI were positively correlated with the occurrence of SCH in T2DM patients(r＞0,P＜0.05).The ROC curve was drawn,and the results showed that the area under the curve(AUC)values of HGI and HbA1c for T2DM patients complicated with SCH were 0.867 and 0.813,respectively,and HGI had the highest evaluation value.Conclusion HGI is related to the occurrence of SCH in T2DM patients.The higher the value,the higher the likelihood of SCH occurrence.
diabetes mellitus type 2glycosylated hemoglobin variation indexsubclinical hypothyroidismcorrelation
万方数据
维普
