Predictive Value of Preoperative Spectral CT Multi-parameter Imaging for Lymph Node Metastasis in Patients with Advanced Lung Cancer
Objective To explore the predictive value of preoperative spectral CT multi-parameter imaging for lymph node metastasis in advanced lung cancer patients.Methods Retrospective collection of clinical data from 60 patients with advanced lung cancer diagnosed through surgical and pathological examination in the hospital from January to June 2023.All patients underwent preoperative spectral CT multi-parameter imaging examination.The results of surgical pathology was set as the gold standard,receiver operating characteristic(ROC)curve was drawn to analyze the value of spectral CT multi-parameter imaging parameters in predicting lymph node metastasis in advanced lung cancer patients.Results After surgical and pathological examination,it was confirmed that among 60 advanced lung cancer patients,19 had lymph node metastasis and 41 had non-lymph node metastasis.The parameters of lymph node HU curve slope(λHU),lymph node λHU/primary lesion λHU,lymph node normalized iodine concentrations(NIC),lymph node NIC/primary lesion NIC,lymph node Neff-Z/primary lesion Neff-Z in patients with lymph node metastasis were lower than patients without lymph node metastasis,and the parameters of primary lesionλHu and primary lesion NIC were higher than patients without lymph node metastasis(P＜0.05).The results of ROC curves showed that the area under the curve of lymph node metastasis in advanced lung cancer patients evaluated by lymph nodeλHU/primary lesion λHU,lymph node NIC/primary lesion NIC and lymph node Neff-Z/primary lesion Neff-Z parameters were all greater than 0.7,which had certain predictive value.Conclusion Preoperative application of spectral CT multi-parameter imaging is helpful in diagnosing lymph node metastasis in advanced lung cancer patients,and preoperative use of spectral CT multi-parameter imaging has certain predictive value for lymph node metastasis in advanced lung cancer patients.
万方数据
维普
