Application Effect and Economic Evaluation of Analgesia Drug After Knee Arthroplasty
Objective To investigate the drug efficacy and economic evaluation of analgesia after knee replacement.Methods A total of 180 patients who underwent knee arthroplasty in our hospital from January 2021 to December 2022 were selected as the study subjects,and were divided into group A(postoperative analgesia with flurbiproxen),group B(postoperative analgesia with parexib)and group C(postoperative analgesia with ketorolac tromethamine)according to random number table method,with 60 cases each.The analgesic effect,visual analogue pain scale(VAS),first time to get out of bed after surgery,PCIA compression times within 48 hours,knee motion and incidence of adverse reactions were compared.Results Repeated measurement analysis of variance showed that there were statistically significant differences between group,time and interaction effects in VAS score at rest and cough,the existence time of knee motion in the three groups(P＜0.05).The resting VAS scores and coughing VAS scores at T1,T2,T3 and T4 in group C were lower than those in group A and group B,respectively,while the knee joint motion at T0,T1,T2,T3,T4 and T5 were higher than those in groups A and B(P＜0.05).The total satisfaction of analgesia in group C was higher than that in groups A and B(P＜0.05).The first time of getting out of bed and the number of PCIA compressions within 48 hours in group C were lower than those in group A and group B(P＜0.05).The length of hospital stay in group C was shorter than that in groups A and B(P＜0.05).The hospitalization cost and analgesic medical cost in groups B and C were lower than those in group A(P＜0.05).There was no significant difference in hospitalization cost and analgesic medical cost between group B and group C(P＞0.05).There was no significant difference in the total incidence of adverse reactions among the three groups(P＞0.05).Conclusion Ketorolac tropanol analgesia after knee joint replacement is beneficial to reduce pain and shorten the first time of getting out of bed.
万方数据
维普
