Application Effect of In-hospital Preparation of Safflower Extract in Enhancing CT Contrast Agent Extravasation
Objective This study aims to explore the clinical efficacy of in-hospital preparation of safflower extract in the treatment of contrast agent extravasation,and compare it with magnesium sulfate wet compress treatment.Methods Due to the intolerance of some patients to magnesium sulfate wet compress treatment,this study attempted to find an effective alternative drug.Therefore,this study included 60 study subjects who received safflower extract(30 cases)and magnesium sulfate wet compress treatment(30 cases),and evaluated the treatment effect.The differences in clinical total effective rate,limb swelling value and pain grade score after 24 hours,72 hours and 1 week of treatment were compared.Results After treatment with safflower extract for 24 hours,72 hours and 1 week,the total clinical effective rates were 80.0％,90.0％and 100.0％,respectively.The total clinical effective rates of magnesium sulfate wet compress treatment after 24 hours,72 hours and 1 week were 80.0％,86.6％and 96.6％,respectively.The swelling values of the affected limb at each treatment time point with safflower extract were(22.79±0.56),(18.24±0.01)and(17.38±0.46)cm,respectively.The swelling values of the affected limb at each treatment time point with magnesium sulfate wet compress were(23.35±0.44),(18.11±0.15),and(17.53±0.27)cm,respectively.The pain level scores of the affected limb at each treatment time point of safflower extract were(8.34±0.04),(4.81±0.31)and(3.68±0.51)points,respectively.The pain level scores of the affected limb at each treatment time point of magnesium sulfate wet compress were(8.22±0.01),(4.78±0.15)and(3.56±0.06)points,respectively.There was no statistically significant difference in clinical total effective rate,limb swelling value and pain level score between the two groups after 24 hours,72 hours and 1 week of treatment(P＞0.05).Conclusion In patients who cannot tolerate magnesium sulfate wet compress,safflower extract can be used as a substitute for treatment,achieving the same clinical efficacy.
万方数据
维普
