Value of Total Cholesterol/Triglyceride in Predicting Postoperative Recurrence of Endometriosis
Objective To explore the predictive value of total cholesterol/triglyceride(TC/TG)in postoperative recurrence of endometriosis.Methods Retrospective analysis was conducted to collect the data of 50 patients who had relapsed after laparoscopy in the Department of Gynecology of the First Affiliated Hospital of Zhengzhou University from January 2020 to June 2022,and were included in the recurrence group during the one-year follow-up period after the surgery.The data of 50 patients who completed laparoscopic surgery in the same period but did not relapse after 1 year of follow-up were collected and included in the non recurrence group.All patient data were complete(including demography data,medical records,relevant laboratory examination results,etc.).The demography data and clinical data of patients were recorded,and the detection results of blood lipid indexes[TC,TG,high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),TC/TG]before operation were recorded and compared between the two groups.The receiver operating characteristic(ROC)curve was drawn to analyze the efficacy of each main index in predicting the risk of postoperative recurrence in patients with endometriosis.Results There was no statistical significant difference in the demography characteristics and clinical data between the recurrence group and the non recurrence group(P＞0.05).The preoperative TC and TG levels in the recurrence group were lower than those in the non recurrence group,and the TC/TG ratio was higher than that in the non recurrence group,with a statistical significant difference(P＜0.05).The ROC curve was drawn,the preoperative TC,TG and TC/TG ratios of patients with endometriosis were all effective in predicting the postoperative recurrence risk.AUC was＞0.70,among which the AUC predicted by TC/TG was 0.905,with the highest predictive value.When the cut off value was 4.780,the ideal sensitivity and specificity were higher.Conclusion The preoperative TC,TG,and TC/TG ratio in patients with endometriosis can be used to predict the risk of recurrence after surgery,but the TC/TG ratio has the highest predictive value for the risk of recurrence,and has a better application value.
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