Effect of Ultrasound-Guided Thoracic Paravertebral Block Combined with General Anesthesia in Patients Undergoing Weight Loss Surgery
Objective To explore the clinical effect of ultrasound-guided thoracic paravertebral block combined with general anesthesia in weight loss surgery.Methods A prospective study included 80 patients who underwent laparoscopic gastric sleeve resection at Zhengzhou Central Hospital Affiliated to Zhengzhou University from June 2020 to August 2023.They were randomly divided into two groups using a random number table method,with 40 patients in each group.The control group received intravenous inhalation combined to general anesthesia,while the observation group received ultrasound-guided thoracic paravertebral block in addition to the control group.Stress response indicators[adrenaline(E),norepinephrine(NE)]and hemodynamics[heart rate(HR),mean arterial pressure(MAP)]were compared between two groups of patients at entry(T0),skin incision(T1),and postoperative(T2).Pain severity was evaluated using visual analogue scale(VAS)at 6,12,and 24 hours after surgery.The occurrence of anesthesia related complications within 72 hours after surgery were recorded.Results The overall analysis of stress response and hemodynamics showed differences in inter group,time point and interaction effects(P＜0.05).Intragroup comparison:E,NE,HR,and MAP of the two groups increased compared to T0 at T,and T2,while T2 increased compared to T1(P＜0.05).Inter group comparison:the E,NE,HR,and MAP of the observation group at T1 and T2 were lower than those of the control group(P＜0.05).Overall analysis of postoperative pain:there were differences in inter group,time point and interaction effects(P＜0.05).Intragroup comparison:the VAS scores of the two groups increased at 12 and 24 hours postoperatively compared to 6 hours postoperatively,and increased at 24 hours postoperatively compared to 12 hours postoperatively(P＜0.05).Inter group comparison:the VAS scores of the observation group were lower than those of the control group at all time points after surgery(P＜0.05).The total incidence of anesthesia related complications in the observation group was lower than that in the control group(P＜0.05).Conclusion Ultrasound guided thoracic paravertebral block combined with general anesthesia can reduce stress response,maintain hemodynamic stability,improve analgesic effect,and reduce the incidence of postoperative complications in patients undergoing weight loss surgery.
weight loss surgeryultrasound guidancethoracic paravertebral blockstress responseanalgesic effect
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维普
