Effect of Corona Virus Disease 2019 Infection on Respiratory Function During Painless Gastrointestinal Endoscopy in Patients with Obstructive Sleep Apnea Syndrome
Objective To investigate the effect of corona virus disease 2019(COVID-19)infection on respiratory function during painless gastrointestinal endoscopy in patients with obstructive sleep apnea syndrome(OSAS).Methods Sixty patients who underwent gastroscopy combined with OSAS at the First Affiliated Hospital of Zhengzhou University from January to March 2023 were selected and divided into two groups according to whether been infected with CO VID-19,30 patients in the control group(uninfected group)and 30 patients in the observation group(infected group).The patients'percutaneous arterial oxygen saturation(SpO2),electrocardiogram and blood pressure were monitored.The respiratory depression,fluctuation of vital signs,incidence of adverse reactions and patient satisfaction were compared between the two groups.Results The number of apneas in the observation group was more than the control group,and the total duration of apneas was longer than that in the control group(P<0.05).There was no statistically difference in the incidence of apnea between the two groups(P>0.05).There was no statistically difference in heart rate,SpO2 and mean artery pressure between the two groups and different time points(P>0.05).The incidence of bradycardia in the observation group was higher than that in the control group(P<0.05).There was no statistically difference in the incidence of hypotension and nausea and vomiting and patient satisfaction between the two groups(P>0.05).Conclusion COVID-19 infection can increase the number of apneas,prolong the total duration of apnea,and increase the risk of respiratory depression in patients with OSAS undergoing painless gastrointestinal endoscopy.