首页|颈动脉狭窄患者颈动脉内膜剥脱术后发生神经损伤的影响因素

颈动脉狭窄患者颈动脉内膜剥脱术后发生神经损伤的影响因素

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目的 探讨颈动脉狭窄患者颈动脉内膜剥脱术后神经损伤发生的影响因素.方法 回顾性收集2020年1月至2023年1月在医院接受颈动脉内膜剥脱术治疗的90例颈动脉狭窄患者的临床资料,依据术后神经损伤发生情况分为发生组(18例)和未发生组(72例).比较两组临床资料,采用logistic回归分析影响颈动脉狭窄患者颈动脉内膜剥脱术后神经损伤发生的因素.结果 发生组性别、年龄、体重指数、高血压、糖尿病、冠心病、高脂血症、吸烟史、饮酒史、手术部位、颈动脉阻断时间、术中使用转流管与未发生组比较,差异无统计学意义(P>0.05);发生组重度颈动脉狭窄、外周动脉疾病史、术前血清同型半胱氨酸(Hcy)水平与未发生组比较,差异有统计学意义(P<0.05);logistic回归分析结果显示,重度颈动脉狭窄、外周动脉疾病史、术前血清Hcy水平是颈动脉狭窄患者颈动脉内膜剥脱术后神经损伤发生的危险因素(OR>1,P<0.05).结论 颈动脉狭窄患者颈动脉内膜剥脱术后神经损伤发生的影响因素主要包括重度颈动脉狭窄、外周动脉疾病史、术前血清Hcy水平.
Influencing Factors of Nerve Damage After Carotid Endarterectomy in Patients with Carotid Artery Stenosis
Objective To explore the influencing factors of nerve damage in patients with carotid artery stenosis after carotid endarterectomy.Methods Clinical data of 90 patients with carotid artery stenosis treated with carotid endarterectomy in the hospital from January 2020 to January 2023 were retrospectively collected.According to the occurrence of postoperative nerve damage,they were divided into occurrence group(18 cases)and non-occurrence group(72 cases).The clinical data of two groups were compared,and the factors affecting the occurrence of nerve injury after carotid endarterectomy in patients with carotid artery stenosis were analyzed by logistic regression.Results There was no statistical difference in gender,age,body mass index,hypertension,diabetes,coronary heart disease,hyperlipidemia,smoking history,drinking history,operation site,carotid artery blocking time,use of bypass tube during operation between the two groups(P>0.05).History of severe carotid artery stenosis,peripheral artery disease and preoperative serum homocysteine(Hcy)levels of the two groups had statistical significant difference(P<0.05).Through logistic regression analysis,the results showed that severe carotid artery stenosis,history of peripheral artery disease and preoperative serum Hcy levels were risk factors for postoperative nerve damage in patients with carotid artery stenosis after carotid endarterectomy(OR>1,P<0.05).Conclusion The influencing factors of postoperative nerve damage in patients with carotid artery stenosis after carotid endarterectomy mainly include severe carotid artery stenosis,history of peripheral artery disease,and preoperative serum Hcy levels.

carotid artery stenosiscarotid endarterectomyneurological injuryinfluence factor

秦跃辉

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濮阳市人民医院血管外科,河南濮阳 457000

颈动脉狭窄 颈动脉内膜剥脱术 神经损伤 影响因素

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(8)
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