Effect of Drug-Coated Balloon and Ordinary Balloon Dilatation on Short-Term and Long-Term Prognosis in Patients with Coronary Heart Disease and In-stent Restenosis
Objective To explore and analyze the effect of drug-coated balloon(DCB)and ordinary balloon dilatation on short-term and long-term prognosis in patients with coronary heart disease and in-stent restenosis.Methods A total of 120 patients with coronary artery disease and in-stent restenosis after interventional therapy in the First People's Hospital of Shangqiu from January 2021 to January 2022 were selected and divided into DCB group and ordinary group,with 60 cases in each group by the random number table method.The DCB group was treated with DCB while the ordinary group was given ordinary balloon dilatation.The dilatation success rate and myocardial markers[creatine kinase myocardial band(CK-MB),troponin T]after treatment,minimum lumen diameter immediately after surgery,late lumen loss,incidence rate of in-stent restenosis and incidence rates of major adverse cardiovascular events(MACE)(cerebral stroke,heart failure,nonfatal myocardial infarction)after 12 months of follow-up were compared between the two groups.Results After treatment,the success rate of dilatation in DCB group(95.00％)was higher than that in ordinary group(83.33％)(P＜0.05).After treatment,the levels of CK-MB and troponin T in DCB group were(12.86±2.45)U·L-1 and(0.12±0.02)μg·L-1,which were lower compared with(15.45±2.48)U·L-1 and(0.22±0.04)µg·L-1 in ordinary group(P＜0.05).The minimum lumen diameter immediately after surgery in DCB group was longer than that in ordinary group[(2.45±0.12)mm vs(2.06±0.04)mm](P＜0.05).After 12 months of follow-up review of coronary angiography,the late lumen loss with(0.26±0.04)mm in DCB group was lower than(0.38±0.08)mm in ordinary group(P＜0.05).The incidence rate of in-stent restenosis in DCB group(5.00％)after 12 months of follow-up was lower than that in ordinary group(16.67％)(P＜0.05).The total incidence rate of MACE in DCB group(16.67％)was lower than that in ordinary group(33.33％)(P＜0.05).Conclusion Drug-coated balloon in the treatment of coronary artery in-stent restenosis in patients with coronary artery disease has a better clinical effect,less late lumen loss,lower incidence rate of in-stent restenosis and more significantly reduced MACE than ordinary balloon dilatation.
万方数据
维普
