Influencing Factors of Reduced Nutritional Status in Patients with Gynecological Malignant Tumor Undergoing Chemotherapy
Objective To investigate the reduction of nutritional status in patients with gynecological malignant tumor undergoing chemotherapy and explore its influencing factors.Methods A total of 247 patients with gynecological malignant tumor undergoing chemotherapy in Xinxiang Central Hospital(the Fourth Clinical College of Xinxiang Medical College)from March 2023 to July 2023 were selected,clinical data of the patients were collected,their nutritional status was investigated,and the nutritional status of the patients was assessed by patient-generated subjective global assessment(PG-SGA).Patients with scores ≥2 were defined as nutrient-impaired and included in the reduced group,whereas those with no nutritional impaired were included in the non-reduced group.By comparing the clinical data of the two groups,lasso was used to screen out the indicators related to the reduction of nutritional status of patients,and logistic multifactor regression was applied to analyze the influencing factors of the reduction of nutritional status of patients with gynecological malignant tumor undergoing chemotherapy.Results In 247 patients with gynecological malignancies treated with chemotherapy,the incidence of decreased nutritional status was 30.36％(75/247),and the rates of suspicious malnutrition,moderate malnutrition and severe malnutrition were 21.33％(16/75),54.67％(41/75)and 24.00％(18/75),respectively.Six predictors were selected by lasso regression analysis,and logistic multivariate analysis showed that TNM stage,economic level,diet status in the previous week,taste change,depression,serum albumin was the influence factor of reduced nutritional status in patients with gynecological malignant tumor undergoing chemotherapy(P＜0.05).Conclusion The reduction of nutritional status of patients with gynecological malignant tumor undergoing chemotherapy is affected by depression,TNM stage,taste change and other factors,so medical workers can implement targeted nursing to improve the nutritional status of patients.
万方数据
维普
