Predictive Ability of Chest Thin-Layer CT for Postoperative Recurrence/Metastasis of Early Invasive Lung Adenocarcinoma
Objective To investigate the predictive ability of chest thin-layer CT in postoperative recurrence/metastasis of early invasive lung adenocarcinoma(IAC).Methods A retrospective study was conducted on 120 patients with early IAC admitted to the Third Affiliated Hospital of Xinxiang Medical University from January 2020 to January 2023.They were divided into two groups(24 cases)and 96 cases(96 cases)according to whether recurrence/metastasis occurred after operation.The results of chest thin-layer CT were compared between the two groups.The predictive value of chest thin-layer CT in postoperative recurrence/metastasis was analyzed by receiver operating characteristic(ROC)curve,and the results of chest thin-layer CT in patients with different pathological subtypes were compared.Results The occurrence of cavitation,vascular,bronchial,pleural indentation and burr signs in the group with lung nodules was higher than that in the group without lung nodules(P＜0.05).Among the chest thin-layer findings,the area under the curve(AUC)of CT value ratio predicting the postoperative recurrence/metastasis was 0.814.The CT value/volume had the highest sensitivity for predicting recurrence/metastasis.The pleural indentation and burr signs had the highest specificity for predicting recurrence/metastasis.The CT value/volume,pleural indentation combined with burr signs had the highest AUC for predicting recurrence/metastasis,with a value of 0.924.The frequency of cavitation sign in the mainly adherent type was higher than that in the mainly non-adherent type,and the frequency of pleural indentation sign and lobulated sign in the mainly non-adherent type was higher than that in the mainly adherent type(P＜0.05).The long diameter of solid components in patients with micropapillae was greater than that in patients without micropapillae(P＜0.05).Conclusion Some imaging characteristics of chest thin-layer CT are associated with early pathological subtypes of IAC and postoperative recurrence/metastasis.The combined application of CT value/volume,pleural indentation sign and spiculation sign has certain predictive value for postoperative recurrence/metastasis,and can be used as an effective examination method for clinical evaluation of postoperative recurrence/metastasis and pathological subtypes.
万方数据
维普
