Effect of Minimally Invasive Vitrectomy in the Treatment of Proliferative Diabetic Retinopathy and the Factors on Postoperative Vitreous Rebleeding
Objective To observe the clinical efficacy of minimally invasive vitrectomy(MIV)in the treatment of proliferative diabetic retinopathy(PDR),and analyze the risk factors for postoperative vitreous hemorrhage(PVH).Methods A total of 286 patients with PDR who were diagnosed and treated in General Hospital of Pingmei Shenma Group from January 2019 to June 2022 were selected as the research subjects.The clinical information were analyzed.The patients were divided into PVH group and non-PVH group according to the presence or absence of PVH.Multivariate logistic regression analysis was performed to screen the risk factors for PVH in patients with PDR.Results The operation time of 286 patients was(66.36±12.74)minutes and electrocoagulation hemostasis times was(1.26±0.21).No bleeding was observed during operation.There were statistically differences in the best corrected visual acuity(BCVA)and intraocular pressure before operation and at 3 months after operation(P＜0.05).The incidence rates of PVH,hyphema and concurrent cataract were 11.54％,0.67％and 2.80％,respectively.Logistic regression analysis found that the course of diabetes mellitus(DM),hypertension and intravitreal sterile air filling were risk factors for PVH in patients with PDR.Age and intravitreal injection of anti-vascular endothelial growth factor(VEGF)drugs after operation were protective factors(P＜0.05).Conclusion MIV is markedly effective in the treatment of PDR as it can promote visual recovery and lower intraocular pressure,with few postoperative complications.Age,duration of DM,hypertension,intravitreal sterile air filling and intravitreal injection of anti-VEGF drugs after operation are influencing factors of PVH in patients with PDR,which deserves attention in clinical practice.
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维普
