Pathogenesis of Patients with Acute Aortic Dissection
Objective The relevant characteristics of acute aortic dissection were analyzed.Methods A retrospective analysis was performed on 239 patients with acute aortic dissection treated from July 2021 to June 2023 in 5 grade Ⅲ and class A hospitals in Zhengzhou City,Henan Province,including age,sex,time of onset(day distribution,season distribution),first clinical symptoms,risk factors,treatment and outcome,hospitalization operation cost,and average length of stay.Results The ratio of male to female with acute aortic dissection was 2.85:1.There was no significant difference between men and women with aortic dissection classification(x2=0.895,P=0.368).The age of onset was(53.79±13.53)years old,while the average age of onset of male and female patients was(51.64±12.91)and(59.92±13.47)years old,respectively(t=4.005,P＜0.001).The age of onset of patients with Stanford A was(52.10± 13.41)years,which was statistically significant compared with that in patients with Stanford B(56.44±13.36)years(t=2.363,P=0.020).The incident was different with the alternation of day and night,seasons.The number of people suffering from the disease was relatively flat from 0:00 to 6:00,while the number starts to increase from 6:00 to 12:00 and reaches the peak from 12:00 to 18:00,then gradually drops from 18:00 to 24:00.The incidence rate was higher in winter,spring and autumn,while it was lower in summer.There was 196 patients with the chest,back or abdominal pain among the first symptom of 239 patients with acute aortic dissection,while 189 patients had a history of hypertension.The hospitalization cost of Stanford A after surgery was(245.8±6.3)thousand yuan,and the hospitalization days were(17.85±10.92)days.While the hospitalization cost of Stanford type B patients was(174.1±5.5)thousand yuan,and the hospitalization days were(17.26± 11.84)days.Conclusion The number of male patients with acute aortic dissection is greater than that of female patients,the incidence of male patients is relatively young,and the incidence is on the rise.Chest,back or abdominal pain is as the first symptom of most acute aortic dissection.Hypertension is an independent risk factor.The correlation between smoking,drinking,diabetes and acute aortic dissection remains to be further confirmed.Surgical treatment is still the key to reduce the mortality of this kind of disease,and with the improvement of the diagnosis and treatment technology of aortic dissection,the in-hospital mortality is gradually decreasing.
万方数据
维普
