Effect of Modified VPS on Hydrocephalus After Intraventricular Hemorrhage and Effect on Nerve Function,Ferric Ion and Aquaporin-4
Objective To investigate the value of modified ventriculoperitoneal shunt(VPS)in the treatment of hydrocephalus after intraventricular hemorrhage(IVH).Methods A total of 102 patients with IVH hydrocephalus in Luoyang Central Hospital from January 2021 to January 2023 were selected and divided into two groups with 51 cases each by simple randomization method.The control group was treated with traditional VPS,and the study group was treated with improved VPS.Surgery-related indexes were compared between the two groups,as well as neurological function scores[(National Institutes of Health stroke scale,NIHSS)]and related factors[albumin quotient(QAlb),neuron-specific enolase(NSE)],serum ferric ion(Fe),aquaporin-4(AQP-4)levels,cognitive function[Montreal cognitive assessment scale(MoCA)scores],ability to lead a life[activities of daily living(ADL)score],and gait disturbance score(Tinetti score),and to compare the rates of complications and good condition at 6 months postoperatively between the two groups.Results The ventilation time,hospitalization time,and hospitalization cost of the study group were lower than those of the control group(P＜0.05).The NIHSS score,cerebrospinal fluid NSE and QAlb,and serum Fe and AQP-4 levels of the study group were lower than those of the control group on the 7 th postoperative day(P＜0.05).The MoCA score,ADL score,and Tinetti score of the study group were higher than those of the control group on the 6th postoperative month(P＜0.05).The study group had a lower complication rate and a higher rate of good prognosis at 6 months postoperatively than the control group(P＜0.05).Conclusion Modified VPS in the treatment of IVH hydrocephalus can reduce neurological damage,restore cognitive function and gait,enhance daily survival,improve prognosis,reduce complications and hospital stay,and reduce the burden of patients.
hydrocephalus after ventricular hemorrhageventriculoperitoneal shuntnerve functioncognitive functioniron ionaquaporin-4ability to liveprognosis
万方数据
维普
