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老年白内障患者超声乳化术后并发干眼症的影响因素

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目的 探讨老年白内障患者超声乳化术后干眼症发生的影响因素,并建立风险预测模型,为临床制定预防措施提供参考.方法 回顾性选取2020年5月至2023年5月郑州大学第一附属医院收治的102例老年白内障患者为研究对象,依据超声乳化术后3个月是否发生干眼症分为发生组(62例)、未发生组(40例),比较两组临床资料,分析干眼症发生的影响因素.结果 糖尿病、超声乳化时间≥20 min、Emery晶状体核硬度分级、入院时泪液白介素-1β(IL-1β)、白介素-8(IL-8)水平为干眼症发生的独立危险因素(P<0.05).结论 糖尿病、超声乳化时间≥20 min、Emery晶状体核硬度分级及入院时泪液IL-1β、IL-8水平为老年白内障患者超声乳化术后干眼症发生的独立危险因素,临床可依据上述因素制定防控措施,以减少干眼症发生.
Influencing Factors of Dry Eye Syndrome After Phacoemulsification in Elderly Cataract Patients
Objective To investigate the factors affecting the occurrence of dry eye in elderly cataract patients after phacoemulsification,and establish a risk prediction model,so as to provide reference for clinical prevention measures.Methods A total of 102 elderly cataract patients admitted to the First Affiliated Hospital of Zhengzhou University from May 2020 to May 2023 were retrospectively selected as the study objects.According to whether dry eye occurred 3 months after phacoemulsification,they were divided into occurrence group(62 cases)and non-occurrence group(40 cases).Clinical data of the two groups were compared to analyze the influencing factors of dry eye.Results Diabetes mellitus,ultrasound emulsification time ≥20 min,Emery lens nuclear hardness grading,and tear fluid interleukin-1β(IL-1β)and interleukin-8(IL-8)levels at admission were independent risk factors for the development of dry eye(P<0.05).Conclusion Diabetes,phacoemulsification time≥20 min,Emery lens nucleus hardness rating and tear IL-1 at admission β、IL-8 levels are an independent risk factor for dry eye syndrome in elderly cataract patients after phacoemulsification.Clinical prevention and control measures can be developed based on these factors to reduce the occurrence of dry eye syndrome.

cataractultrasound emulsification surgerydry eye syndromeinfluence factor

刘方方、杜佳文、李亚楠

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郑州大学第一附属医院眼二科,河南郑州 450000

白内障 超声乳化术 干眼症 影响因素

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(10)
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