Clinical Efficacy of EECP Combined with Intensive Lipid-lowering on Patients After PCI and Its Effect on Residual Inflammatory Factors
Objective To observe the clinical efficacy of enhanced external counterpulsation(EECP)combined with intensive lipid-lowering on patients after percutaneous coronary intervention(PCI)and its effect on residual inflammatory factors.Methods One hundred and fifty patients who attended the Department of Cardiovascular Medicine of the Second Affiliated Hospital of Zhengzhou University from June 2021 to June 2023 and met the inclusion criteria were selected.They were randomly divided into three groups,A,B and C with 50 patients in each group respectively.Group A was given conventional drug therapy,group B was given conventional drug therapy and intensive lipid-lowering therapy,and group C was given conventional drug therapy and intensive lipid-lowering therapy and EECP treatment.The changes of clinical efficacy,activity tolerance,cardiac ejection function and residual inflammatory factors were compared between the three groups after treatment.Results After the treatment,the frequency and duration of angina attacks,residual inflammatory factor hypersensitive C-reactive protein and lipoprotein correlation phospholipase A2 levels of the three groups of patients were lower than those before treatment,and the indexes of Group C were significantly less than those of Groups A and B,with a statistically significant difference(P＜0.05).After the treatment,the 6-minute walking experimental distance and left ventricular ejection fraction of the patients of the three groups were all increased than those before treatment,and the increase was more obvious in group C patients,with statistically significant differences(P＜0.05).Conclusion EECP combined with intensive lipid-lowering can effectively improve the clinical symptoms,increase activity tolerance and improve cardiac ejection function of patients after PCI.Inhibition of the expression of the levels of residual inflammatory factors may be one of its mechanisms of the action.
万方数据
维普
