Effect of acupoint Thread Embedding Combined with Tiaozhi Anxin Tang on the Treatment of Coronary Heart Disease Combined with Hyperlipidemia
Objective To observe the effect of acupoint thread embedding combined with Tiaozhi Anxin tang on the treatment of coronary heart disease complicated with hyperlipidemia.Methods Eighty patients with coronary heart disease complicated with hyperlipidemia admitted to the hospital from May 2022 to May 2023 were selected as the study subjects and randomly divided into two groups using a random number table method.The routine Western medicine group received symptomatic treatment according to the routine Western medicine plan,while the comprehensive Western and Chinese medicine group received traditional Chinese medicine comprehensive therapy combining acupoint embedding and Tiaozhi Anxin tang on the basis of the Western medicine plan.After treatment,the clinical efficacy was analyzed,and the differences of lipid metabolism,chemokine Fractalkine(CX3CL1),monocyte chemokine protein-1(MCP-1),heart function,milk fat globule-epidermal growth factor 8(MFG-E8)and TCM syndrome scores before and after treatment were compared.Results The total effective rate of the integrated Chinese and Western medicine group was higher than that of the conventional Western medicine group(P＜0.05).There was no statistically difference in lipid metabolism,CX3CL1,MFG-E8,and MCP-1 between the two groups before treatment(P＞0.05).The levels of triglyceride(TG),CX3CL1,total cholesterol(TC),MCP-1,and low-density lipoprotein cholesterol(LDL-C)in the integrated Chinese and Western medicine group and the conventional Western medicine group were lower than before,with lower levels in the integrated Chinese and Western medicine group(P＜0.05).The levels of high-density lipoprotein cholesterol(HDL-C)and MFG-E8 in the integrated Chinese and Western medicine group and the conventional Western medicine group were higher than before,and the integrated Chinese and Western medicine group was higher(P＜0.05).There was no statistically difference in heart function and traditional Chinese medicine syndrome scores between the two groups before treatment(P＞0.05).The CI,SV,CO,and LVEF of the two groups increased compared to before,with higher values in the integrated Chinese and Western medicine group(P＜0.05).The main symptoms,secondary symptoms,and tongue pulse scores of the integrated Chinese and Western medicine group and the conventional Western medicine group decreased compared to before,while the integrated Chinese and Western medicine group had lower scores(P＜0.05).Conclusion Acupoint catgut embedding combined with Tiaozhianxin Decoction can regulate the expression of CX3CL1,MFG-E8 and MCP-1,improve lipid metabolism and cardiac function,and improve the curative effect of coronary heart disease complicated with hyperlipidemia.
acupoint embeddingcoronary heart diseaseregulating fat peace of mind souphyperlipidemiaheart functionlipid metabolism
万方数据
维普
