首页|中医特色情志疗法对焦虑抑郁合并失眠患者睡眠质量、心理调适及单胺类神经递质水平的影响

中医特色情志疗法对焦虑抑郁合并失眠患者睡眠质量、心理调适及单胺类神经递质水平的影响

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目的 探讨中医特色情志疗法在焦虑抑郁合并失眠中的临床效果.方法 选取开封市中医院2021年4月至2023年4月收治的116例患者,按照随机数字表法分组,各58例.对照组接受西医常规治疗,情志组在此基础上接受中医特色情志疗法.比较两组治疗效果、中医证候积分、焦虑抑郁情绪[汉密尔顿焦虑、抑郁量表(HAMA、HAMD)]、睡眠质量[匹兹堡睡眠指数量表(PSQI)]、心理调适能力[心理复原力量表(CD-RISC)]、单胺类神经递质水平.结果 情志组总有效率高于对照组(P<0.05);治疗3个月后情志组入睡困难/易醒、情绪抑郁、神疲乏力、头昏头痛、胸胁满闷、纳差积分低于对照组(P<0.05),HAMA、HAMD、PSQI评分低于对照组(P<0.05),CD-RISC评分高于对照组(P<0.05),血清多巴胺、5-羟色胺、去甲肾上腺素水平高于对照组(P<0.05).结论 中医特色情志疗法治疗焦虑抑郁合并失眠效果确切,能改善焦虑抑郁情绪,提高心理调适能力、睡眠质量、单胺类神经递质水平,从而提高治疗效果.
Effects of Traditional Chinese Medicine Characteristic Emotional Therapy on Psychological Adjustment,Sleep Quality and Monoamine Neurotransmitter Level in Patients with Anxiety,Depression and Insomnia
Objective To explore the clinical effect of traditional Chinese medicine characteristic emotional therapy on anxiety and depression combined with insomnia.Methods A total of 116 patients admitted to Kaifeng Traditional Chinese Medicine Hospital from April 2021 to April 2023 were selected and divided into groups using a random number table method,with 58 patients in each group.The control group received routine western medicine treatment,while the emotional group received traditional Chinese medicine characteristic emotional therapy on this basis.The treatment effects,traditional Chinese medicine syndrome scores,anxiety and depression emotions[Hamilton anxiety and depression scale(HAMA,HAMD)],sleep quality[Pittsburgh sleep index(PSQI)],psychological adjustment ability[psychological resilience scale(CD-RISC)],and levels of monoamine neurotransmitters between two groups were compared.Results The total effective rate of the emotional group was higher than that of the control group(P<0.05).After 3 months of treatment,the emotional group had difficulty falling asleep/waking up,emotional depression,fatigue,dizziness and headache,chest and rib fullness,and lower anorexia score than the control group(P<0.05).The HAMA,HAMD,and PSQI scores were lower than the control group(P<0.05),and the CD-RISC score was higher than the control group(P<0.05).The serum levels of dopamine,5-hydroxytryptamine,and norepinephrine were higher than the control group(P<0.05).Conclusion The traditional Chinese medicine characteristic emotional therapy has a definite therapeutic effect on anxiety and depression combined with insomnia,which can improve anxiety and depression emotions,enhance psychological adjustment ability,sleep quality,and levels of monoamine neurotransmitters,thereby improving the treatment effect.

emotional therapyanxietydepressioninsomniasleep qualitymonoamine neurotransmitters

许梁洁、王清峰、寇绍杰、王振坤

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开封市中医院脑病科,河南开封 475000

情志疗法 焦虑 抑郁 失眠 睡眠质量 单胺类神经递质

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(10)
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