Effect of Shengjiang Decoction on Chronic Atrophic Gastritis with Liver Depression and Spleen Weakness
Objective To explore the effect of Shengjiang decoction on chronic atrophic gastritis patients with liver depression and spleen weakness.Methods A prospective randomized controlled study was conducted.From January 2022 to May 2023,90 patients with chronic atrophic gastritis with liver depression and spleen weakness in the First Affiliated Hospital of Xinxiang Medical University were selected as the research objects.According to the random number table method,they were divided into control group(45 cases)and treatment group(45 cases).The control group was treated with conventional western medicine,and the treatment group was treated with Shengjiang decoction on the basis of the control group.Both groups were treated for 4 consecutive weeks.The clinical efficacy of the two groups was observed,and the improvement of traditional Chinese medicine syndrome scores,gastroscopy performance and gastric mucosal biopsy pathological atrophy before and after treatment were compared between the two groups.Results The total effective rate of the treatment group(95.56％)was higher than that of the control group(80.00％)(P＜0.05).After treatment,the traditional Chinese medicine syndrome score[(epigastric distension and(or)dull pain,low belching,chest tightness,noisy acid reflux,fatigue,loose stool or constipation)]of the treatment group was lower than that in the control group(P＜0.05).The atrophic gastritis performance scores under gastroscopy of the treatment group after treatment were lower than those of the control group(P＜0.05).The gland atrophy,intestinal metaplasia and chronic inflammation scores of the two groups after treatment were lower than those before treatment,and the treatment group was lower than the control group(P＜0.05).Conclusion Shengjiang decoction has significant effect on chronic atrophic gastritis patients with liver depression and spleen weakness,which can significantly improve the traditional Chinese medicine syndromes and the performance of atrophic gastritis under gastroscopy in patients with chronic atrophic gastritis,reverse gastric mucosal atrophy to a certain extent,and delay the progression of the disease.
chronic atrophic gastritisliver depression and spleen weaknessShengjiang decoctionmechanism of action
万方数据
维普
