Relationship Between Serum Residual Cholesterol,Triglyceride-Glucose Index and H-type Hypertension
Objective To explore the relationship between serum residual cholesterol(RC),triglyceride glucose(TyG)index and young patients with H-type hypertension.Methods A total of 290 young hypertensive patients admitted to the Huazhong Cardiovascular Hospital in Fuwai from January 2020 to April 2023 were collected as the experimental group.Based on serum homocysteine(Hey)levels,the experimental group was further divided into an H-type hypertension group of 170 cases and a normal Hey hypertension group(pure hypertension group)of 120 cases.Another 90 healthy individuals who underwent physical examinations during the same period were selected as the normal control group.The Cobas8000 fully automatic biochemical analyzer was used to detect biochemical indicators such as Hey,blood lipids,and renal function in three groups of blood samples.Single factor analysis of variance was used to compare the differences in levels among the three groups.Pearson correlation method was used to analyze the correlation between Hey and total cholesterol(TC),RC,TyG,blood urea nitrogen(BUN),creatinine(Cr),and uric acid(UA).Multiple logistic regression analysis was used to identify the influencing factors of H-type hypertension patients.Results The levels of BUN,Cr,UA,and GFR in the H-type hypertension group and the simple hypertension group were higher than those in the normal control group,and the H-type hypertension group showed an upward trend compared to the simple hypertension group,with statistical significance(P＜0.05).The levels of CHO,RC,and TyG in the H-type hypertension group and the simple hypertension group were higher than those in the normal control group,and the H-type hypertension group showed an upward trend compared to the simple hypertension group,with statistical significance(P＜0.05).Multivariate logistic regression analysis found that gender,RC,TyG,BUN,Cr,UA were the influencing factors for high Hey in patients with H-type hypertension.Conclusion High Hey in patients with H-type hypertension is associated with TyG and RC levels.Clinical treatment measures can be taken based on the patient's TyG and RC levels to prevent the occurrence of H-type hypertension.
type H hypertensionhomocysteinetriglyceride glucose indexremnant cholesterol
万方数据
维普
