Effect of Different Femoral Nerve Block in Hip Fracture Patients
Objective To compare the sedative and analgesic effects of ropivacaine and ropivacaine combined with dexmedetomidine on the stability of vital signs and stress response in patients with hip fracture.Methods Using a random number table method,102 patients who were admitted to Luoyang Orthopaedic-Traumatological Hospital of Henan Province/Henan Provincial orthopedic Hospital from February 2020 to February 2023 and scheduled for hip fracture internal fixation were divided into group A and group B,with 51 cases in each group.Group A received femoral nerve block with 3.75 g·L-1 ropivacaine,while group B received femoral nerve block with 3.75 g·L-1 ropivacaine combined with dexmedetomidine.The surgical conditions(intraoperative blood loss,operation time and hospital stay)were compared between the two groups.Taking the time points of pre-operative(T0)and post-operative positioning(T,)as the time nodes,the levels of vital signs indicators[heart rate(HR),mean arterial pressure(MAP)]and visual analog scale(VAS)were compared between the two groups.The scores of observer's assessment of alert/sedation scale(OAA/S)were compared between the two groups.Taking T0 and 24 hours after surgery(T2)as the time nodes,the levels of stress factors[norepinephrine(NE),epinephrine(E),cortisol(Cor)]were compared between the two groups.Results The length of hospital stay in group B was less than that in group A(P＜0.05).The HR,MAP levels and VAS score in group B were lower than those in group A at T1,while the OAA/S score was higher than that in group A at T,(P＜0.05).Compared with the group A,the NE,E and Cor levels in group B were lower at T2(P＜0.05).The total incidence of adverse reactions between group A and group B had no significantly different(P＞0.05).Conclusion The use of ropivacaine combined with dexmedetomidine for femoral nerve block during hip fracture surgery can enhance sedation and analgesia,stabilize hemodynamic levels,reduce stress response,and ensure safety.
万方数据
维普
