Objective To systematically evaluate the clinical safety and effectiveness of Daqinglong decoction in the adjuvant treatment of asthma in pediatric patients.Methods A computer search was performed on Wanfang database,CNKI database,CBM database,VIP database,Cochrane Library and PubMed,and controlled trials designed for Daqinglong decoction on children with asthma were randomized.Two independent evaluators selected the trials and evaluated the quality respectively.After extracting valid data,meta-analysis was performed using RevMan 5.3.3 software.Results A total of 19 controlled clinical trials were included,and 1 472 cases were collected.The meta-analysis results showed that there was a statistically difference in the total effective rate,forced expiratory volume at 1 second(FEV1),forced vital capacity(FVC),FEV1/FVC and wheezing syndrome score between the simple conventional treatment group and the Daqinglong decoction adjuvant treatment group(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Daqinglong decoction has obvious therapeutic effect on asthma children,although the adverse drug reaction is slight and the safety factor is high,but more high-quality,rigorous,multicentre,large sample controlled trial is needed to verify it.
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