Comparison of Safety Between Afentanil and Sufentanil for Non Intubated General Anesthesia Thoracoscopic Wedge Resection of the Lung in Patients
Objective To compare the safety of afentanil and sufentanil in non intubated general anesthesia thoracoscopic wedge resection of the lung.Methods A retrospective analysis was conducted to collect data from 40 patients who underwent non intubated general anesthesia thoracoscopic lung wedge resection with afentanil at the First Affiliated Hospital of Zhengzhou University from January 2022 to December 2023,and were included in the afentanil group.Data from 40 patients who underwent non intubated thoracoscopic wedge resection using sufentanil at the same time in the hospital were collected and included in the sufentanil group.The patient's medical records,surgical data,and other related information had been fully preserved,and the non intubated general anesthesia thoracoscopic wedge resection of the lung had been completed.Data of patients were collected,patient hemodynamics[mean arterial pressure(MAP)and heart rate(HR)before anesthesia,skin cutting,and awake],perioperative indicators(time of anesthesia onset,recovery time,recovery time of spontaneous breathing),and adverse reactions were recorded and compared.Results There was no difference in MAP and HR between the afentanil group and the sufentanil group before anesthesia,during skin cutting,and during wakefulness(P＞0.05).Compared to before anesthesia,MAP and HR decreased during skin cutting,while MAP and HR increased during wakefulness compared to skin cutting(P＜0.05).The onset time,awakening time,and spontaneous breathing recovery time of the afentanil group were shorter than those of the sufentanil group(P＜0.05),and the incidence of adverse reactions in the afentanil group was lower than that in the sufentanil group(P＜0.05).Conclusion Alfentanil and sufentanil are equally effective in stabilizing patient hemodynamic parameters during non intubated thoracoscopic wedge resection under general anesthesia.However,compared to afentanil,it has a faster onset of action and allows patients to wake up and regain spontaneous breathing in a short period of time after surgery,with fewer adverse reactions and higher safety when used.
non intubated general anesthesiathoracoscopic wedge resection of lungafentanilsufentanilhemodynamicssecurity
NETL
NSTL
万方数据
