Research Progress in the Management of Sarcopenia in Patients with Liver Cirrhosis
Cirrhosis predisposes to abnormalities in energy,hormonal,and immunological homeostasis.Disturbances in these metabolic processes create susceptibility to sarcopenia or pathological muscle wasting.Sarcopenia is prevalent in cirrhosis.Its presence portends significant adverse outcomes including the length of hospital stay,infectious complications,and mortality.This highlights the importance of identification of at-risk individuals with early nutritional,therapeutic and physical therapy intervention.This manuscript summarizes literature relevant to sarcopenia in cirrhosis,describes mechanism,evaluation methods and intervention measures for sarcopenia.