Therapeutic Effect of Minimally Invasive Surgery on Perifocal Edema of Spontaneous Cerebral Hemorrhage
Objective To explore the therapeutic effect of minimally invasive surgery on perifocal edema of spontaneous cerebral hemorrhage and its impact on brain edema index and cerebrospinal fluid level,in order to provide theoretical basis for optimizing treatment plans in clinical practice.Methods A prospective randomized controlled study was conducted,selecting 78 patients with spontaneous cerebral hemorrhage combined with edema around the bleeding site from June 2020 to June 2022 as the study subjects.The study group was divided into an observation group(39 cases)and a control group(39 cases)using a random number table and sealed letter method.The control group received craniotomy and large bone flap decompression surgery,while the observation group received stereotactic surgical aspiration treatment.The surgical efficacy of the two groups was observed 3 months after operation.The perioperative indexes(operation and hospitalization time)of the two groups were recorded.The cerebral edema index,cerebrospinal fluid level[interleukin-1β(IL-1β),S-100 calcium binding protein β(S-100β)]and postoperative complications were compared between the two groups before and 14 days after operation.Results Three months after surgery,the clinical efficacy of the observation group was better than that of the control group,with a statistical significant difference(P＜0.05).The observation group had shorter surgical and hospital stays compared to the control group,with a statistical significant difference(P＜0.05).On the 5th day after surgery,the brain edema index of both groups of patients decreased,and the observation group was smaller than the control group,with a statistical significant difference(P＜0.05).The levels of IL-1β and S-100β in the cerebrospinal fluid of both groups of patients decreased,and the observation group was lower than the control group 14 days after surgery,with a statistical significant difference(P＜0.05).Both groups of patients experienced postoperative complications,but there was no statistical significant difference between the groups(P＞0.05).Conclusion Minimally invasive surgery can effectively treat perifocal edema of spontaneous cerebral hemorrhage,improve the degree of brain edema,and reduce the degree of brain injury,which is worthy of clinical promotion and application.
spontaneous cerebral hemorrhageedemastereotactic surgerycraniotomy and large bone flap decompression
万方数据
维普
