Correlation Between Renal Function and Sex Hormones,Blood Lipid Metabolism in Menopausal Women
Objective To explore the correlation between renal function and sex hormones,blood lipid metabolism in postmenopausal women.Methods A total of 100 menopausal women undergoing examinations in Zhengzhou Second People's Hospital were enrolled as the research objects between August 2021 and July 2023.According to estimated glomerular filtration rate(GFR),they were divided into normal group(63 cases)and impaired renal function group(37 cases).The levels of serum sex hormones(estradiol,follicle-stimulating hormone)and blood lipid metabolism(fasting blood glucose,total cholesterol,triacylglycerol,high density lipoprotein cholesterol,low density lipoprotein cholesterol)in both groups were detected,and their correlation with renal function was analyzed.Results The levels of serum follicle-stimulating hormone and low density lipoprotein cholesterol in impaired renal function group were higher than those in normal group,while levels of estradiol,high density lipoprotein cholesterol were lower than those in normal group(P＜0.05).Spearman rank correlation test showed that serum estradiol,high density lipoprotein cholesterol were positively correlated with renal function,while follicle-stimulating hormone and low density lipoprotein cholesterol levels were negatively correlated with it(P＜0.05).Multivariate linear regression analysis showed that age,estradiol,follicle-stimulating hormone,high density lipoprotein cholesterol,and low density lipoprotein cholesterol were all independent influencing factors of renal function in postmenopausal women(P＜0.05).Conclusion The disordered sex hormones and abnormal blood lipid metabolism are correlated with declined renal function in postmenopausal women.
万方数据
维普
