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双相情感障碍患者发生自杀行为的高危因素及预防措施

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目的 探讨双相情感障碍患者发生自杀行为的高危因素及预防措施.方法 回顾性分析2021年1月至2022年12月商丘市第二人民医院收治的134例双相情感障碍患者的临床资料,根据所选患者是否有发生自杀行为将其分为自杀组(41例)和无自杀组(93例).比较两组临床资料,将单因素分析中有统计学意义的因素纳入多因素分析,并通过多因素logistic回归分析法分析影响双相情感障碍患者发生自杀行为的高危因素.结果 自杀组女性、有精神刺激史、冲动性格、有重大精神创伤、既往有非自杀性自伤、既往有自杀未遂的患者占比均高于无自杀组(P<0.05),首发年龄小于无自杀组(P<0.05),血清游离三碘甲状腺原氨酸(FT3)水平低于无自杀组(P<0.05).多因素logistic回归分析结果显示,女性、有重大精神创伤、首发年龄小、血清FT3水平低是影响双相情感障碍患者发生自杀行为的独立危险因素(P<0.05).结论 女性、有重大精神创伤、首发年龄小、血清FT3水平低是影响双相情感障碍患者发生自杀行为的独立危险因素,可据此给予高危患者相应的治疗及干预措施,以减少自杀事件的发生.
High Risk Factors and Preventive Measures for Suicidal Behavior in Patients with Bipolar Disorder
Objective To explore the high risk factors and preventive measures of suicidal behavior in patients with bipolar disorder.Methods The clinical data of 134 patients with bipolar disorder admitted to the Second People's Hospital of Shangqiu from January 2021 to December 2022 were retrospectively analyzed.The selected patients were divided into the suicide group(41 cases)and the non-suicide group(93 cases)according to whether they had suicidal behavior.The clinical data of the two groups were compared,and the factors with statistical significance in the univariate analysis were included in the multivariate analysis,and the risk factors affecting the suicidal behavior of patients with bipolar disorder were analyzed by multivariate logistic regression analysis.Results The proportion of patients with women,with history of mental stimulation,impulsive personality,major mental trauma,previous non-suicidal self-injury and previous suicide attempt in the suicide group were higher than the non-suicide group.The first onset age were smaller than the non-suicide group.Levels of serum free triiodothyronine(FT3)were lower than those in the non-suicide group(P<0.05).Multivariate logistic regression analysis showed that female,major mental trauma,young age at first onset and low level of serum FT3 were independent risk factors for suicidal behavior in patients with bipolar disorder(P<0.05).Conclusion Female,major trauma,young age at first episode and low level of serum FT3 were independent risk factors for suicidal behavior in patients with bipolar disorder.Accordingly,appropriate treatment and intervention measures could be given to high-risk patients to reduce the occurrence of suicide events.

bipolar disordersuicidehigh risk factor

刘杰

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商丘市第二人民医院精神科十病区,河南商丘 476000

双相情感障碍 自杀 高危因素

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(14)
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