Trend of Clinical Epidemiological Characteristics of Breast Cancer in Xinxiang Central Hospital from 2003 to 2020
Objective To analyze the changing trend of epidemiological characteristics of breast cancer in Xinxiang Central Hospital from 2003 to 2020,in order to provide reference for the prevention,treatment and research of breast cancer in Xinxiang.Methods Clinical and pathological datas of female patients with primary breast cancer who were diagnosed and hospitalized for the first time in Xinxiang Central Hospital from 2003 to 2020 were collected,and a database of breast cancer patients was established.The clinical characteristics and trends of inpatients with female breast cancer,such as the number of cases,age of diagnosis,clinical stage,molecular classification and surgical methods were analyzed retrospectively.Results A total of 5 451 inpatients with female breast cancer were admitted,of which 5 097 patients were included in the age analysis,and the median age of diagnosis was 52 years old,with a high prevalence age between 46-50 years old(948 cases,17.39％).The proportion of ≤ 35 years old(young breast cancer patients)was 5.32％(271 cases),and the proportion of ≤ 25 years old(very young breast cancer patients)was 0.24％(12 cases).The clinical stages were mainly stage Ⅰ(24.91％)and stage Ⅱ(49.44％).A total of 3 947 patients with complete and accurate pathological datas were included in molecular typing analysis,including 2 838(71.90％)Luminal type,590(14.95％)triple-negative type,and 519(13.15％)HER-2 positive type.The main surgical methods were modified radical mastectomy,breast conserving surgery appeared in 2010,and the proportion of breast conserving surgery increased from 0.36％in 2010 to 21.91％in 2020.Sentinel lymph node biopsy began in 2015,and the proportion of implementation increased from 13.54％in 2015 to 57.57％in 2020.Conclusion The number of female breast cancer inpatients in Xinxiang Central Hospital from 2003 to 2020 showed an increasing trend year by year.The high incidence age was 46-50 years old,and the median age of diagnosis showed an increasing trend.The proportion of young breast cancer patients was stable.The clinical stages were mainly early stage,the proportion of stage Ⅰ increased,the proportion of stage Ⅲ decreased,and the proportion of stage 0 and stage Ⅳ remained stable.The number of Luminal breast cancer patients accounted for the largest proportion,and showed an increasing trend year by year.The proportion of breast conserving operation and sentinel lymph node biopsy increased year by year.
breast cancermonocentricepidemiology featuretendency
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