Characteristics of Endoscopic Precision Examination and the Efficacy of Endoscopic Resection Treatment for Rectal Neuroendocrine Tumors
Objective To explore the characteristics of endoscopic endoscopy of rectal neuroendocrine tumors and observe the efficacy and safety of patients undergoing endoscopic resection.Methods This study was conducted in 60 patients with rectal neuroendocrine tumors treated in the First Affiliated Hospital of Xinxiang Medical College from January 2020 to January 2024,and the characteristics of endoscopic precision examination were recorded.Patients were grouped using envelope method,30 patients received endoscopic submucosal dissection(ESD)treatment and were included in the ESD group,while 30 patients received endoscopic mucosal resection(EMR)treatment and were included in the EMR group,and their lesion resection,clinical surgical data,quality of life and complications were recorded.Results Among the 60 patients with rectal neuroendocrine tumors,the male proportion was relatively high,the age was under 60 years old,the tumor size was more than 5 mm,and far away from the anus,and the WHO classification was G1.The curative resection rate and whole piece resection rate of ESD group were higher than those of EMR group(P＜0.05),but there was no statistical difference in the residual rate between groups(P＞0.05).Operation time and postoperative hospital stay of ESD group were longer than EMR group,and wound diameter was greater than EMR group(P＜0.05),but there was no statistical difference in specimen diameter and thickness(P＞0.05).There was no statistically difference in the quality of life scores between the two groups before treatment(P＞0.05).After 7 days of treatment,the quality of life scores in both groups decreased compared to before treatment,and ESD group was lower than EMR group(P＜0.05).There was no statistically difference in the incidence of postoperative delayed bleeding,perforation,subcutaneous emphysema,local recurrence,and infection between the two groups(P＞0.05).Conclusion The majority of patients with rectal neuroendocrine tumors are under 60 years old,with a higher proportion of males.The tumor size is mostly ≥5 mm,and the distance from the anus is mostly ≥5 cm.Immunohistochemical results show a higher proportion of Syn positive patients.ESD treatment can improve the curative resection rate,overall resection rate,and quality of life,but the patient's surgical time and postoperative hospitalization time are longer than EMR,and the wound diameter is larger.Therefore,the treatment plan should be flexibly selected according to clinical practice.
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