Value of Uterine Artery Pulsatility Index,Pre-pregnancy Body Mass Index and Mean Artery Pressure in Predicting Adversepregnancy Outcomes in Low-risk Pregnant Women in the Second Trimester
Objective To assess the value of second trimester mean artery pressure(MAP),pre-pregnancy body mass index(BMI)combined with uterine artery pulsatility index(PI)in predicting adverse pregnancy outcomes in low-risk pregnant women.Methods The demographic,clinical,uterine artery Doppler ultrasound parameters and pregnancy outcomes of 148 low-risk pregnant women admitted to the prenatal clinic of our hospital at 21-25 weeks of gestation were retrospectively analyzed and divided into two groups according to their pregnancy outcomes,the normal pregnancy outcome group(99 patients)and the adverse pregnancy outcome group(49 patients).Results Univariate analysis revealed significant differences in age,pre-pregnancy BMI,MAP,and uterine artery PI(P＜0.05),and there were no significant differences in parameters such as times of pregnancy,actual gestational weeks,biparietal diameter,femoral length,maximum depth of amniotic fluid,uterine artery resistance index(RI),uterine artery S/D,and termination of gestational weeks between the normal pregnancy outcome group and the adverse pregnancy outcome group(P＞0.05).Multivariate analysis showed that pre-pregnancy BMI,MAP,and uterine artery PI were significant factors affecting adverse pregnancy outcomes.Based on these findings,a prediction model for adverse pregnancy outcomes was constructed.Receiver operating characteristic(ROC)curve analysis showed that the area under the curve(AUC)of the model to predict adverse pregnancy outcomes was 0.730,with a sensitivity of 81.63％,and a specificity of 55.56％.Conclusion Second trimester uterine artery PI combined with pre-pregnancy BMI and MAP has certain clinical predictive value for adverse pregnancy outcomes in low-risk pregnant women.
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