Clinical Effect of Modified Shengjiang Powder in the Treatment of Herpangina Children with Heat Accumulation of Heart and Spleen
Objective To investigate the clinical effect of modified Shengjiang Powder on herpangina(HA)in children with heat accumulation syndrome of heart and spleen.Methods From March 2022 to March 2023 in Zhumadian Hospital of Traditional Chinese Medicine,117 children with heart and spleen heat syndrome HA were selected and divided into interferon group(58 cases,treated with human interferon α-2b spray)and traditional Chinese medicine group(TCM group,59 cases,treated with modified Shengjiang Powder combined with human interferon α-2b spray)according to treatment methods.The efficacy,symptom improvement,inflammatory index and immune function index were compared between the two groups.Results After treatment,the improvement time of fever,herpes disappearance,salivation and appetite recovery in TCM group was shorter than that in interferon group(P＜0.05).After treatment,the serum levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and C-reactive protein(CRP)in TCM group were lower than those in interferon group(P＜0.05).After treatment,the levels of immunoglobulin A(IgA),immunoglobulin G(IgG)and immunoglobulin M(IgM)in TCM group were higher than those in interferon group(P＜0.05).The total effective rate of TCM group(98.31％)was higher than that of interferon group(84.48％)(P＜0.05).Conclusion Modified Shengjiang Powder can improve the treatment efficiency,improve clinical symptoms,reduce the level of inflammation and improve the immune function of children with herpetic pharyngitis.
herpetic pharyngobuccinitisheat accumulation syndrome of heart and spleenchildrenmodified Shengjiang Powderinflammationimmune function
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