Risk Factors for MACE After PCI in Patients with Acute Non-ST-Segment Elevation Myocardial Infarction
Objective To discuss the risk factors for major adverse cardiovascular events(MACE)within 1 years after percutaneous coronary intervention(PCI)in acute non-ST-segment elevation myocardial infarction(NSTEMI).Methods The clinical data of 213 NSTEMI patients admitted to the Cardiology Department of the First Affiliated Hospital of Soochow University from January 2019 to January 2022 were collected.All patients were followed up through outpatient clinics and telephone,and they were divided into non-MACE group(without MACE,170 cases)and MACE group(with MACE,43 cases)according to the follow up results.And single and multivariate analysis was conducted on two groups to explore the independent risk factors for MACE after PCI in NSTEMI patients.Results Single factor analysis showed that the proportion of hypertension,diabetes and the number of diseased branches≥2 increased in the MACE group,and the global registration of acute coronary events(GRACE)risk score,red blood cell distribution width(RDW),prothrombin time(PT)at admission were higher than those in the non-MACE group,while the hemoglobin and total cholesterol(TC)levels at admission were lower than those in the non-MACE group(P＜0.05).The results of binary logistic regression analysis showed that the number of diseased branches ≥2(OR=2.172,95％CI:1.291-3.653,P＜0.05),GRACE risk score(OR=1.035,95％CI:1.019-1.050,P＜0.05),diabetes(OR=2.705,95％CI:1.114-6.567,P＜0.05)and RDW(OR=2.145,95％CI:1.250-3.681,P＜0.05)were independent risk factors for MACE in NSTEMI patients after PCI.The results of receiver operating characteristic curve analysis showed that the area under the curve of GRACE risk score was 0.799(P＜0.001)and cut-off value was 147.5 points,the area under the curve of RDW was 0.693(P＜0.001)and cut-off value was 13.05％.Conclusion The number of diseased branches ≥ 2,GRACE score,diabetes and increased RDW level are independent risk factors for the occurrence of MACE events in NSTEMI patients after PCI.Hypertension,hemoglobin,TC and PT levels have certain predictive value for the occurrence of MACE.
万方数据
维普
