Effect of Modified Erchen Decoction on Childhood Obesity
Objective To explore the curative effect of modified Erchen Decoction on childhood obesity.Methods A prospective study was conducted on 104 children with obesity admitted to Zhumadian Traditional Chinese Medicine Hospital from January 2022 to June 2023.They were randomly divided into a control group(52 cases received regular aerobic exercise intervention)and a study group(52 cases received modified Erchen Tang treatment on the basis of the control group)using a random number table method.The treatment lasted for 2 months,and the efficacy,body mass index and waist circumference,internal biochemical indicators,and endothelial function indicators were compared between the two groups.Results Compared with the control group,the total effective rate of the study group was higher(P＜0.05).Compared with before treatment,the body mass index and waist circumference of both groups decreased after 1 and 2 months of treatment,and the study group had even lower values(P＜0.05).Compared with before treatment,after 2 months of treatment,both groups showed a decrease in total cholesterol,triglyceride,low-density lipoprotein cholesterol,fasting insulin and leptin,while high-density lipoprotein cholesterol increased(P＜0.05).Compared with the control group,the study group had lower levels of total cholesterol,triglyceride,low-density lipoprotein cholesterol,fasting insulin,leptin,and higher level of high-density lipoprotein cholesterol(P＜0.05).Compared with before treatment,after 2 months of treatment,nitric oxide and endothelial dependent vasodilation function of both groups increased,and endothelin decreased.Compared with the control group,the study group had higher level of nitric oxide and endothelial dependent vasodilation,and lower levels of endothelin(P＜0.05).Conclusion The modified Erchen Decoction has a good curative effect on childhood obesity,which can effectively reduce the body mass index and waist circumference of patients and improve endogenous biochemical indexes and endothelial function.
modified Erchen Decoctionchildhood obesitytherapeutic effectendobiochemical indexendothelial function
万方数据
维普
