High Risk Factors of Pulmonary Infection in Patients with Diabetic Nephropathy Undergoing Hemodialysis
Objective To analyze the relevant factors affecting the occurrence of pulmonary infections in diabetic nephropathy(DN)patients undergoing hemodialysis,and to incorporate the risk factors into logistic regression analysis,establish a prediction model,and explore the predictive value,so as to provide reference for the rational development of clinical preventive programs.Methods A total of 102 cases of hemodialysis patients with DN were collected from March 2020 to December 2022 in Huaihe Hospital of Henan University,which were divided into 48 cases in the infection group and 54 cases in the control group according to pulmonary infection.Univariate and logistic regression were applied to analyze the relevant factors affecting pulmonary infection in hemodialysis patients with DN,and predictive models was constructed to analyze predictive value.Results Multivariate logistic regression analysis showed that age ≥60 years(OR=1.692,P＜0.05),malnutrition(OR=2.038,P＜0.05),whole blood level of fasting blood glucose ≥ 14 mmol·L-1(OR=4.104,P＜0.05)and serum level of albumin＜35 g·L-1(OR=3.374,P＜0.05)were independent high risk factors.Receiver operating characteristic(ROC)curve analysis showed that when prediction probability logit(P)＞9.75,the area under the curve(AUC)was 0.871,the 95％CI was 0.790-0.929,the sensitivity was 70.83％,and the specificity was 92.59％.Conclusion Pulmonary infections in DN patients on hemodialysis are associated with age,malnutrition,whole blood fasting glucose and serum albumin levels.The related prediction model could accurately predict pulmonary infection in patients with DN hemodialysis,and has high clinical application value.
diabetic nephropathyhemodialysispulmonary infectionhigh risk factorprediction modelprediction value
万方数据
维普
