Drug Resistance Analysis of Secondary Vaginal Infection in Dysfunctional Uterine Bleeding
Objective To analyze the status of secondary vaginal infection and drug resistance in dysfunctional uterine bleeding(DUB)and to provide theoretical basis for clinical treatment.Methods A total of 145 patients with secondary vaginal infection of DUB were selected from Jiyuan People's Hospital from December 2020 to December 2022.The secretions from the posterior fornix and cervix of the vagina were collected,and the distribution of pathogenic bacteria was analyzed and the drug resistance of main pathogenic bacteria was understood through the culture of pathogenic bacteria and drug susceptibility test.Results In 145 vaginal secretion specimens,a total of 237 pathogenic strains were isolated,including 45 gram-positive(18.99％),49 gram-negative(20.68％),82 fungal(34.60％),and 61 Mycoplasma(25.74％)strains.The sensitivity of Streptococcus agalactia and Enterococcus faecalis to ampicillin,linezolid and minocycline were 100％.The sensitivity of Escherichia coli and Klebsiella pneumoniae to teicoplanin was 100％.The sensitivity of Candida albicans and Candida glabrata to amphotericin B and nystatin were 100％.Mycoplasma were sensitive to sparfloxacin.Conclusion The main pathogens in patients with secondary vaginal infection of DUB are bacteria,fungi and Mycoplasma,all of which are resistant to antibiotics to varying degrees.It is recommended that hospitals strengthen supervision,give sensitive antibiotics treatment,avoid relapse and long-term drug use as much as possible,and reduce the occurrence of drug-resistant strains.
万方数据
维普
