首页|不同时机进行颅骨修补对重型颅脑损伤患者神经功能、脑血流状态的影响

不同时机进行颅骨修补对重型颅脑损伤患者神经功能、脑血流状态的影响

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目的 研究不同时机进行颅骨修补对重型颅脑损伤患者神经功能、脑血流状态的影响.方法 选取2021年1月至2023年7月河南中医药大学第一附属医院收治的80例重型颅脑损伤患者,随机分为常规组(40例)和研究组(40例),常规组于去骨瓣减压术(DC)后3~6个月进行颅骨修补,研究组于DC术后4~6周进行颅骨修补,3个月后收集研究数据并对比两组患者术后脑血流状态、并发症情况、神经功能、日常生活能力.结果 手术后,研究组大脑后动脉(PCA)、大脑中动脉(MCA)、大脑前动脉(ACA)血流速度均高于常规组(P<0.05);手术后,研究组美国国立卫生研究院卒中量表(NIHSS)评分低于常规组(P<0.05);手术后,研究组Barthel指数(BI)评分高于常规组(P<0.05);常规组、研究组并发症发生率分别为10.00%、12.50%,两组并发症发生率差异无统计学意义(P>0.05).结论 于DC术后4~6周进行颅骨修补能够更好改善重型颅脑损伤患者脑血流状态,促进神经功能恢复,提高日常生活能力,安全性高,具有临床推广价值.
Effects of Skull Repair at Different Times on Nerve Function and Cerebral Blood Flow in Patients with Severe Craniocerebral Injury
Objective To study the effects of skull repair at different times on nerve function and cerebral blood flow in patients with severe craniocerebral injury.Methods A total of 80 patients with severe craniocerebral injury in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from January 2021 to July 2023 were randomly divided into the conventional group(40 cases)and the study group(40 cases).The conventional group received skull repair 3-6 months after decompressive craniotomy(DC),and the study group received skull repair 4-6 weeks after DC surgery.Study data were collected and compared between the two groups with postoperative cerebral blood flow status,complications,neurological function and daily living ability.Results After surgery,the blood flow velocity of posterior cerebral artery(PCA),middle cerebral artery(MCA)and anterior cerebral artery(ACA)were higher than those in conventional group(P<0.05).After surgery,the National Institutes of health stroke scale(NIHSS)score of the study group was lower than that of the conventional group(P<0.05).After operation,the Barthel index(BI)score of the study group was higher than that of the conventional group(P<0.05).The incidence of complications in the conventional group and the study group was 10.00%and 12.50%,respectively,and there was no statistical difference between the two groups(P>0.05).Conclusion Skull repair 4-6 weeks after DC surgery can better improve cerebral blood flow status in patients with severe craniocerebral injury,promote neurological function recovery,improve daily living ability,and have high safety and clinical value.

skull repaircraniocerebral injurycerebral blood flow statusdifferent timesnerve functionability of daily living

简历、魏振宇、司东明、杨冬谊

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河南中医药大学第一附属医院(河南中医药大学第一临床医学院)神经外科,河南郑州 450000

颅骨修补 颅脑损伤 脑血流状态 不同时机 神经功能 日常生活能力

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(22)