Establishment and Clinical Value Analysis of Nomogram Prediction Model for Exposure Keratitis After Upper Eyelid Ptosis Correction Surgery
Objective To investigate the risk factors for the development of exposure keratitis after ptosis correction,to develop a nomogram model for predicting the development of exposure keratitis,and to analyze the clinical value of its application.Methods A total of 165 patients who underwent ptosis correction surgery in Zhengzhou Second People's Hospital from January 2021 to June 2023 were collected as study subjects.Independent risk factors derived from the multifactorial analysis were used to create a column-line graphical model.The discrimination and consistency of the model were verified by receiver operating characteristic(ROC)curve and calibration curves,and the scope of clinical application of the model was assessed by decision curve analysis(DCA).Results Univariate analysis showed no statistically differences between the exposed keratitis group and unexposed keratitis group in terms of gender and age(P>0.05),whereas the differences were statistically significant compared to Bell's sign,number of repairs,dry eye,surgical procedure,and corneal contact lenses(P<0.05).The multivariate results showed negative Bell's sign,number of repairs ≥ 1,dry eye,frontal muscle suspension,and not wearing corneal contact lenses were the independent risk factors for the development of exposure keratitis after ptosis correction.The area under the curve(AUC)of the ROC was 0.840,with a high degree of discrimination.The calibration curves showed high consistency,and the DCA results indicated that the nomogram model has good utility and safety in predicting the occurrence of postoperative exposure keratitis.Conclusion Bell's sign negative,repair times ≥1,dry eye,no contact lens wearing,and frontal muscle suspension can be considered as independent risk factors for exposure keratitis.The Nomogram model based on these factors has high accuracy and has high clinical application value for predicting the occurrence of exposed keratitis.
ptosis of the upper eyelidexposure keratitisregression analysiscolumn chart model