Application of Remifentanil Combined with Sevoflurane in Spinal Surgery Under General Anesthesia
Objective To analyze the application effect of remifentanil combined with sevoflurane in spinal surgery under general anesthesia.Methods Medical records of 48 patients who underwent spinal surgery under general anesthesia at Henan Province Veterans Hospital from January 2022 to June 2023 were collected and included in the control group.Medical records of 48 patients who received remifentanil combined with sevoflurane anesthesia for spinal surgery under general anesthesia in the same hospital during the same period were collected and included them in the observation group.All clinical data of patients had been fully preserved.The analgesic and sedative effects,hemodynamic indexes and recovery effects at different time points[before anesthesia(T0),before intubation(T1),5 min after intubation(T2),and at the end of operation(T3)]of both groups were compared.The postoperative adverse reactions were compared in both groups.Results The difference was not statistically significant in sedation satisfaction between observation group and control group(P＞0.05).Compared with control group,the visual analogue scale(VAS)scores of the observation group were lower at 4,6,12,and 24 hours after surgery(P＜0.05).The mean arterial pressure and heart rate at T1,T2 and T3 in the two groups were lower than those before operation,but the observation group was higher than the control group(P＜0.05).There was no differences in heart rate and mean arterial pressure at each time point between the two groups(P＞0.05).Compared with control group,the recovery time of directional force,respiratory recovery time,extubation time,and awakening time of the observation group patients were shorter(P＜0.05).There were no differences in the incidence of postoperative adverse reactions between the two groups of patients(P＞0.05).Conclusion Remifentanil combined with sevoflurane has good sedative and analgesic effects in spinal surgery under general anesthesia,can maintain stable hemodynamic levels,help patients recover from postoperative anesthesia,and is safe.
万方数据
维普
