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万古霉素不同给药途径治疗感染性眼内炎的效果

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目的 观察万古霉素不同给药途径治疗感染性眼内炎的临床效果.方法 对郑州市第二人民医院2021年1月到2023年9月收入眼科的90例(90眼)感染性眼内炎患者的资料进行回顾性分析.接受玻璃体腔注射联合静脉滴注万古霉素治疗的患者纳入观察组,仅接受玻璃体腔注射万古霉素治疗的患者纳入对照组.比较两组患者的致病原因、入院视力及治疗结果.结果 观察组和对照组在患者性别、年龄、致病因素和入院视力等方面差异无统计学意义(P>0.05).经万古霉素治疗后,患者出院时视力差异无统计学意义(P>0.05).结论 万古霉素治疗感染性眼内炎有效.两种治疗方案效果相当,提示临床可采用仅玻璃体腔注射万古霉素治疗感染性眼内炎,减少医疗操作,降低药物不良反应,节约医疗费用.
Effect of Different Administration Routes of Vancomycin in the Treatment of Infectious Endophthalmitis
Objective To observe the clinical efficacy of different administration routes of vancomycin in the treatment of infectious endophthalmitis.Methods A retrospective analysis was conducted on the data of 90 patients(90 eyes)with infectious endophthalmitis admitted to the Zhengzhou Second Hospital from January 2021 to September 2023.Patients who received intravitreal injection combined with intravenous infusion of vancomycin were included in the observation group,while patients who only received intravitreal injection of vancomycin were included in the control group.The pathogenic factors,admission visual acuity,and treatment outcomes of the two groups of patients were compared.Results There was no statistically difference in gender,age,pathogenic factors,and admission vision between the observation group and the control group(P>0.05).After treatment with vancomycin,there was no statistically difference in visual acuity between patients at discharge(P>0.05).Conclusion Vancomycin is effective in treating infectious endophthalmitis.The two treatment plans have similar effects,indicating that only intravitreal injection of vancomycin can be used in clinical treatment of infectious endophthalmitis,reducing medical procedures,reducing adverse drug reactions,and saving medical expenses.

infective endophthalmitisvancomycinintravitreal injection

张颖、孙玉鹤、韩露、张慧芝

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郑州市第二人民医院药学部,河南郑州 450006

感染性眼内炎 万古霉素 玻璃体腔注射

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(23)