Diagnostic Value of Electrocardiogram for Left Ventricular Hypertrophy in Cardio-Oncology Patients
Objective To investigate the clinical value of the electrocardiogram in diagnosing left ventricular hypertrophy(LVH)in cardio-oncology patients.Methods From January 1 to December 31,2023,1 824 hypertensive patients with LVH on routine electrocardiogram examination at Henan Cancer Hospital were selected and simultaneously underwent echocardiography.The Cornell criteria,the Peguero-Lo Presti criteria,the RL Ⅰ+SV4 criteria,and the Romhilt-Estes scoring system were used for the electrocardiogram diagnosis of the above patients.The echocardiographic results were seted as the"gold standard",receiver operating characteristic(ROC)curve was drawn to compare the area under the curve,sensitivity,specificity,accuracy,and positive/negative predictive values of the different criteria.Results Among the 1 824 patients with LVH,echocardiography diagnosed 344 patients with LVH and 1 480 patients without LVH.The sensitivity,specificity,and accuracy of the Cornell criteria were 22.67%,91.22%,and 78.29%,respectively.For the Peguero-Lo Presti criteria,they were 42.15%,73.18%,and 67.32%,respectively.For the RL Ⅰ+SV4 criteria,they were 50.29%,61.42%,and 59.32%,respectively.For the Romhilt-Estes scoring system,they were 37.21%,90.88%,and 80.76%,respectively.The area under the ROC curve of the Romhilt-Estes scoring system(0.640)was higher than the Cornell criteria(0.569),the Peguero-Lo Presti criteria(0.577),and the RL Ⅰ+SV4 criteria(0.559)(P<0.01).There were no statistically significant differences among the Cornell criteria,the Peguero-Lo Presti criteria,and the RL Ⅰ+SV4 criteria(P>0.05).Conclusion The Romhilt-Estes scoring system can be used as an electrocardiogram screening method for LVH in cardio-oncology patients and is superior to the other three diagnostic methods.