首页|百令胶囊联合西药治疗COPD稳定期(肺肾气虚证)的效果

百令胶囊联合西药治疗COPD稳定期(肺肾气虚证)的效果

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目的 探讨百令胶囊联合西药在慢性阻塞性肺疾病(COPD)稳定期(肺肾气虚证)患者中的应用效果。方法 选取2020年9月至2021年10月南阳市中心医院收治的84例COPD稳定期患者,采用随机数字表法分为A组、B组,各42例。A组接受常规西药治疗,B组在A组基础上接受百令胶囊口服治疗。结果 治疗8周后较治疗前,两组用力肺活量(FVC)、第1秒用力呼气量(FEV1)、FEV1/FVC、FEV,占预计值百分比(FEV1%)、外周血血氧饱和度(SaO2)、血氧分压(PaO2)水平均升高,B组高于A组(P<0。05)。两组中医证候积分、呼吸困难、生活质量评分、外周血二氧化碳分压(PaCO2)水平均降低,B组低于A组,两组6分钟步行距离(6MWD)均增加,B组高于A组(P<0。05)。随访8周后,较A组,B组急性加重再入院率更低(P<0。05)。结论 百令胶囊联合西药治疗可改善COPD稳定期(肺肾气虚证)患者肺功能,促进患者血气指标的调节,缓解患者临床症状,提高其生活质量及步行能力,控制患者急性加重再入院率,且安全性良好。
Effect of Bailing Capsules Combined with Western Medicine in the Treatment of Stable COPD(Lung and Kidney Qi Deficiency Syndrome)
Objective To explore the application of Bailing capsules combined with Western medicine in patients with chronic obstructive pulmonary disease(COPD)in stable phase(lung and kidney Qi deficiency syndrome).Methods A total of 84 stable COPD patients admitted to Nanyang Central Hospital from September 2020 to October 2021 were selected and randomly divided into group A and group B using a random number table method,with 42 patients in each group.Group A received conventional Western medicine treatment,group B received oral treatment with Bailing capsules on the basis of group A.Results After 8 weeks of treatment,compared to before treatment,the forced vital capacity(FVC),forced expiratory volume in one second(FEV1),FEV1/FVC,FEV1%of expected value(FEV1%),peripheral blood oxyhemoglobin saturation(SaO2),blood partial pressure of oxygen(PaO2)levels in both groups increased,and group B were higher than group A(P<0.05).Traditional Chinese medicine symptoms,dyspnea,quality of life scores and partial pressure of carbon dioxide(PaCO2)levels of two groups decreased,and compared with the group A,the group B were lower.The six-minute walking distance(6MWD)of two groups increased,and group B was higher than group A(P<0.05).After 8 weeks of follow-up,compared with the group A,the group B had a lower rate of acute exacerbation readmission(P<0.05).Conclusion Bailing capsule combined with Western medicine can improve the lung function of COPD patients in stable period(lung and kidney Qi deficiency syndrome),promote the adjustment of blood gas indexes,relieve the clinical symptoms of patients,improve their quality of life and walking ability,control the readmission rate of patients with acute exacerbation,and have good safety.

chronic obstructive pulmonary diseasestable periodlung and kidney Qi deficiency syndromeWestern medicineBailing capsulespulmonary function

孙辉、曾佳、郑大炜

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南阳市中心医院呼吸与危重症医学科一病区,河南南阳 473000

慢性阻塞性肺疾病 稳定期 肺肾气虚证 西药 百令胶囊 肺功能

2024

河南医学研究
河南省医学科学院

河南医学研究

影响因子:0.979
ISSN:1004-437X
年,卷(期):2024.33(24)