首页|腹腔镜联合醋酸戈舍瑞林治疗子宫内膜异位症的临床疗效分析

腹腔镜联合醋酸戈舍瑞林治疗子宫内膜异位症的临床疗效分析

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目的 研讨腹腔镜联合醋酸戈舍瑞林治疗子宫内膜异位症的临床疗效。方法 收集整理2019年7月-2022年4月期间河南科技大学附属许昌市中心医院收治的子宫内膜异位症患者114例,随机分为对照组(n=57,腹腔镜治疗)和联合组(n=57,术后联合醋酸戈舍瑞林治疗),对比两组治疗前后激素水平促卵泡激素(Folli-cle stimulating hormone,FSH)、雌激素(estrogen,E2)、促黄体生成激素(Luteinizing hormone,LH)、妊娠率、输卵管通畅率和复发率情况。结果 治疗后联合组患者E2、LH、FSH水平明显下降,治疗后有效率联合组为94。74%,对照组为82。46%,有效率情况组间对比差异明显。联合组患者妊娠率57。89%,输卵管通畅率91。23%,明显高于对照组的22。81%和47。37%;联合组复发率为1。75%明显低于对照组的29。82%(P<0。05)。结论 腹腔镜联合醋酸戈舍瑞林治疗子宫内膜异位症,受孕率和治疗效果明显提高,复发率下降,安全可靠。
Clinical analysis of laparoscopy combined with goserelin acetate in treatment of endometriosis
Objective To study the clinical efficacy of laparoscopy combined with goserelin acetate in the treatment of endometriosis.Methods Totally 114 cases of endometriosis treated from July 2019 to April 2022 were collected and randomly divided into control group(n=57,treated by laparoscopy)and combined group(n=57,treated by goserelin acetate after operation).The hormone levels Follicle stimulating hormone(FSH),estrogen(Estrogen)were compared before and after treatment.E2,Luteinizing hormone(LH),pregnancy rate,tubal patency rate and recurrence rate.Results After treatment,the levels of E2,LH and FSH in the combined group decreased significantly,and the effec-tive rate was 94.74%in the combined group and 82.46%in the control group,with significant differences between the two groups.The pregnancy rate in the combined group was 57.89%,and the tubal patency rate was 91.23%,which was significantly higher than that in the control group(22.81%and 47.37%).The recurrence rate of the combined group was 1.75%,which was significantly lower than that of the control group(29.82%,P<0.05).Conclusion Laparoscopy combined with goserelin acetate in the treatment of endometriosis can obviously improve the pregnancy rate and therapeutic effect,and reduce the recurrence rate,which is safe and reliable.

EndometriosisSurgical treatmentLaparoscopyGoserelin acetateCombined therapyEffect

曹蒙、郝玉娟、常璐、苏宁

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河南科技大学附属许昌市中心医院,河南许昌 461670

子宫内膜异位症 手术治疗 腹腔镜 醋酸戈舍瑞林 联合治疗 效果

2024

医药论坛杂志
中华预防医学会,河南省医学情报研究所

医药论坛杂志

影响因子:0.47
ISSN:1672-3422
年,卷(期):2024.45(1)
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