首页|男性成人阻塞性睡眠呼吸暂停低通气综合征患者的抑郁与焦虑现状分析以及新冠疫情的影响

男性成人阻塞性睡眠呼吸暂停低通气综合征患者的抑郁与焦虑现状分析以及新冠疫情的影响

扫码查看
目的 探究男性成人阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的抑郁与焦虑情况以及新冠疫情对其的影响。方法 选取2019年3月—2020年8月于郑州大学第二附属医院就诊的符合标准的患者249例。依据睡眠暂停低通气指数(AHI),将患者分为对照组、轻度组、中度组与重度组,轻中度组及重度组又根据疫情暴发时间分为疫情前组(2019年3月-2019年11月)及疫情组(2019年12月—2020年8月)。收集患者的年龄、体质指数(BMI)、颈围、腰围、臀围。采用多导睡眠监测(PSG)检查记录患者的AHI、最低血氧饱和度(LSaO2)、平均血氧饱和度(MSaO2),并完成抑郁自评量表(SDS)及焦虑自评量表(SAS)评分。结果 四组患者的年龄之间无明显差异(P>0。05)。四组患者的BMI、腰围、臀围及颈围之间差异有统计学意义(P<0。001),重度组的各指标均高于轻度组与中度组。四组患者的SDS与SAS标准分之间差异具有统计学意义(P<0。001),重度组的SDS与SAS评分高于轻度组与中度组,轻中度组及重度组中疫情组评分均高于疫情前组,差异有统计学意义(P<0。001)。重度OSAHS患者抑郁与焦虑的共病率高于轻中度组(P<0。001)。OSAHS患者的AHI与SDS评分、SAS评分均呈正相关关系(r值分别为0。387、0。305,P<0。05)。结论 男性OSAHS患者疾病的严重程度可能与其并发抑郁、焦虑有关。与轻、中度患者相比,男性重度OSAHS患者伴发抑郁与焦虑的风险更高,且疫情后风险更加突出,临床需多关注。PSG监测指标AHI与男性OSAHS的抑郁与焦虑评分表现出较好的相关性,其可在一定程度上反映患者抑郁、焦虑情况。
Depression and anxiety status of male adult patients with obstructive sleep apnea hypopnea syndrome and the influence of COVID-19
Objective To explore the depression and anxiety of male adults with obstructive sleep apnea Hypopnea syndrome(OSAHS)and the influence of normal epidemic prevention and control on them.Methods A selection of 249 patients who were hospitalized in the Second Affiliated Hospital of Zhengzhou University from March 2019 to August 2020.According to the sleep apnea-hypopnea index(AHI),patients were divided into control group,mild group,moderate group and severe group.The mild to moderate group and severe group are further divided into the pre epidemic group(March 2019 to November 2019)and the epidemic group(December 2019 to August 2020)based on the outbreak time of the epidemic.Patients age,body mass index(BMI),neck circumference,waist circumference,and hip circumference were collected.Using polysomnography(PSG)checking patient re-cords AHI,the lowest oxygen saturation(LSaO2),the average oxygen saturation(MSaO2),and the Self-Rating Depression Scale(SDS)and Self-Rating Anxiety Scale(SAS)scores were completed.Results There was no significant difference in the age of the four groups of patients(P>0.05).The differences in BMI,waist circumfer-ence,hip circumference and neck circumference of the four groups were statistically significant(P<0.001).The indexes of the severe group were higher than those of the mild group and the moderate group.The difference be-tween the SDS and SAS standard scores of the four groups was statistically significant(P<0.001).The SDSand SAS scores of the severe group were higher than those of the mild group and the moderate group.The scores of the epidemic prevention and control group in the mild to moderate and severe groups were higher than those of the pre epidemic group,and the difference was statistically significant(P<0.001).The comorbidity rate of depression and anxiety in patients with severe OSAHS was higher than that of the mild to moderate group(P<0.001).The AHI of OSAHS patients was positively correlated with SDS score and SAS score(r values were 0.387 and 0.305,respectively,P<0.05).Conclusion The severity of the disease in male OSAHS patients may be related to their concurrent depression and anxiety.Compared with mild to moderate patients,male patients with severe OSAHS have a higher risk of depression and anxiety,and the risk is more prominent after the epidemic,which requires more clinical attention.The PSG monitoring indicator AHI shows a good correlation with the depression and anxiety scores of male OSAHS,which can reflect the depression and anxiety situation of patients to a certain extent.

MaleObstructive sleep apnea hypopnea syndromeDepressionAnxietyEpidemic

张晓萍、张筠、邵润霞

展开 >

郑州大学第二附属医院呼吸与危重症医学科,郑州 450014

男性 阻塞性睡眠呼吸暂停低通气综合征 抑郁 焦虑 新冠疫情

2024

医药论坛杂志
中华预防医学会,河南省医学情报研究所

医药论坛杂志

影响因子:0.47
ISSN:1672-3422
年,卷(期):2024.45(3)
  • 24