Value of acoustic elastography combined with S-Detect technology in diagnosis of benign and malignant TI-RADS type 4 thyroid nodules
Objective To explore the value of acoustic elastography(AE)combined with S-Detect technology in the diagnosis of benign and malignant thyroid imaging reporting and data system(TI-RADS)type 4 thyroid nodules.Methods Totally 80 patients with TI-RADS type 4 thyroid nodules(96 nodules)who admitted to Xuchang People's Hospital from June 2021 to June 2023 were selected as the study subjects.AE and S-Detect technology were used for diagnosis,and pathological diagnosis was used as the gold standard to evaluate the diagnostic efficiency of each examina-tion method in differentiating benign and malignant nodules.Results Surgical pathological examination of 96 nodules showed 64 malignant nodules(66.67％)and 32 benign nodules(33.33％).The average AE score of 64 malignant nodules was(4.31±0.83)points,and that of 32 benign nodules was(2.16±1.25)points.The average AE score of malignant nodules was significantly higher than that of benign nodules(t=10.069,P＜0.001).There were differences between AE diagnosis and pathology in 23 nodules,of which 8 nodules were misdiagnosed,including 5 nodular goiter and 3 follicular adenoma,and 15 nodules were missed,including 9 papillary thyroid carcinoma,5 follicular thyroid car-cinoma and 1 medullary carcinoma.S-Detect technology diagnosis were different from pathology in 15 nodules,among which 5 nodules were misdiagnosed,including 3 nodular goiter and 2 follicular adenomas,and 10 nodules were missed,including 6 papillary thyroid carcinoma,3 follicular thyroid carcinoma and 1 medullary carcinoma.The sensitivity,spe-cificity and accuracy of AE combined with S-Detect technology were 95.31％,84.38％and 91.67％respectively in the differential diagnosis of TI-RADS type 4 thyroid nodules,and the Kappa value of consistency test with pathological diagnosis was 0.81.Conclusion AE combined with S-Detect technology has high efficiency in differentiating benign and malignant TI-RADS type 4 thyroid nodules,and it has good consistency with pathological diagnosis.
Thyroid nodulesThyroid imaging reporting and data systemAcoustic elastographyS-Detect technology
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