目的 对比分析颈动脉体瘤副神经节瘤(carotid body tumor,CBT)与头颈部非颈动脉体瘤副神经节瘤(非CBT)患者的临床特征。方法 通过对郑州大学第一附属医院2014年1月至2021年12月收治的43例头颈部副神经节瘤患者的临床资料进行回顾,对比两组患者的人口学特征、生活方式、临床特征、治疗及预后。结果 CBT组患者女性更常见(P<0。05)。非CBT组患者吸烟史、饮酒史更常见(P<0。05)。非CBT组患者术前影像学检查诊断准确性较CBT组低(P<0。05)。非CBT组患者S-100的阳性表达率低于CBT组(P<0。05)。两组患者治疗均首选外科手术治疗。非CBT组术后并发症发生率(16。28%)高于CBT组(6。98%)(P<0。05)。结论 头颈部副神经节瘤的预后与其发病部位相关;非CBT组患者影像学检查准确性较低,诊断更困难,术后并发症发生率更高。
Comparative analysis of head and neck carotid body tumor and non-carotid body tumor paraganglioma
Objective To compare the clinical characteristics of carotid body tumor paraganglioma(CBT)and head and neck non-carotid body tumor paraganglioma(non-CBT).Methods The clinical data of 43 patients with head and neck paraganglioma admitted to our hospital from January 2014 to December 2021 were reviewed,and the demographic charac-teristics,lifestyle,clinical features,treatment and prognosis of the two groups of patients were compared.Results Women were more common in CBT group(P<0.05).Smoking history and drinking history were more common in the non-CBT group(P<0.05).The diagnostic accuracy of preoperative imaging examination in non-CBT group was lower than that in CBT group(P<0.05).The positive expression rate of S-100 in non-CBT group was lower than that in CBT group(P<0.05).Surgical treatment was the first choice for both groups.The incidence of postoperative complica-tions in non-CBT group(16.28%)was higher than that in CBT group(6.98%)(P<0.05).Conclusion The progno-sis of head and neck paraganglioma is related to the location of the disease.In the non-CBT group,the accuracy of ima-ging examination is lower,the diagnosis is more difficult,and the incidence of postoperative complications is higher.