Effects of pituitrin combined with carprost ambutritol and oxytocin on postpartum hemorrhage after placental abruption
Objective To analyze the effect of pituitrin,carprost ambutriol and oxytocin in the treatment of postpartum hemorrhage after placental abruption.Methods Totally 64 cases of postpartum hemorrhage after placental abruption ad-mitted to the First People's Hospital of Pingdingshan City from May 2019 to May 2021 were divided into four groups by random number table method.32 cases in the control group were treated with caprost triol combined with oxytocin,and 32 cases in the study group were treated with pituitarine on the basis of the control group.The therapeutic effect,post-partum blood loss,hemostasis time,changes in coagulation function indexes,pregnancy outcome,third stage of labor time,hospital stay and incidence of adverse reactions were compared between the two groups.Results The total effec-tive rate of the study group and the control group was 93.75％and 75.00％,respectively,with significant difference be-tween groups(P＜0.05).The postpartum blood loss in the study group was(150.24±18.87)mL in 30min,(202.07±26.69)mL in 2h and(281.12±31.16)mL in 24h,which were all less than those in the control group,and the hemostasis time[(25.26±4.88)min]was shorter than that in the control group.The difference between the two groups was significant(P＜0.05).After treatment,the levels of TT,APTT and FIB in the study group were(18.13±3.22)s,(40.10±10.06)s and(3.15±0.71)g/mL,respectively,which were significantly lower than those in the control group,and the difference between the two groups was significant(P＜0.05).The incidence of ad-verse pregnancy outcome in the study group(3.13％)was lower than that in the control group(18.75％)(P＜0.05).The time of the third stage of labor in the study group was(4.41±1.02)min and the time of hospitalization was(6.62±1.23)d,which were lower than those in the control group(P＜0.05).The incidence of adverse drug reac-tions in the study group(6.25％)was significantly lower than that in the control group(25.00％)(P＜0.05).Conclusion The combined treatment of pituitrin,carprost ambutritol and oxytocin can significantly improve the condi-tion and optimize the pregnancy outcome of puerpera hemorrhage after placental abruption,and the adverse drug reac-tions are less,the treatment safety is guaranteed,this treatment plan is worth promoting in clinical application.
Placental abruptionPostpartum hemorrhagePituitrinCarprost aminobuttriolOxytocinBlood coagulation function
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